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    SEC Form 10-K filed by Alto Neuroscience Inc.

    3/16/26 6:07:28 AM ET
    $ANRO
    Biotechnology: Pharmaceutical Preparations
    Health Care
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    Recent Analyst Ratings for
    $ANRO

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    11/17/2025Buy
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    9/29/2025$15.00Buy
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    Alto Neuroscience Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Other Events, Financial Statements and Exhibits

    8-K - Alto Neuroscience, Inc. (0001999480) (Filer)

    3/16/26 7:08:09 AM ET
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    SEC Form S-8 filed by Alto Neuroscience Inc.

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    3/16/26 6:44:48 AM ET
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    SEC Form 10-K filed by Alto Neuroscience Inc.

    10-K - Alto Neuroscience, Inc. (0001999480) (Filer)

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    PRESIDENT AND CEO Etkin Amit covered exercise/tax liability with 6,227 shares, decreasing direct ownership by 0.50% to 1,233,949 units (SEC Form 4)

    4 - Alto Neuroscience, Inc. (0001999480) (Issuer)

    3/3/26 7:16:05 PM ET
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    CHIEF FINANCIAL OFFICER & CBO Smith Nicholas Conrad covered exercise/tax liability with 2,806 shares, decreasing direct ownership by 10% to 24,060 units (SEC Form 4)

    4 - Alto Neuroscience, Inc. (0001999480) (Issuer)

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    SEC Form 4 filed by PRESIDENT AND CEO Etkin Amit

    4 - Alto Neuroscience, Inc. (0001999480) (Issuer)

    2/13/26 5:20:16 PM ET
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    CHIEF MEDICAL OFFICER Savitz Adam bought $190,833 worth of shares (15,000 units at $12.72) (SEC Form 4)

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    Smith Nicholas Conrad bought $100,628 worth of shares (6,150 units at $16.36), increasing direct ownership by 30% to 26,866 units (SEC Form 4)

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    4/1/24 4:15:30 PM ET
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    Alto Neuroscience Announces $120 Million Private Placement Financing

    – Financing led by Commodore Capital with participation from new and existing biotech focused investors – –  Alto expects to use the proceeds of the financing to support the development of ALTO-207 in Treatment Resistant Depression through a planned Phase 3 study and to a potential NDA submission – Alto Neuroscience, Inc. ("Alto") (NYSE:ANRO), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, announced today that it has entered into a securities purchase agreement with institutional and accredited investors to sell securities in a private placement financing (the "PIPE") for gross proceeds of approximately

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    Alto Neuroscience Reports Full Year 2025 Financial Results and Recent Business Highlights

    – Acquisition of ALTO-207 targets Treatment-Resistant Depression (TRD) with a clinically-validated mechanism; Phase 2b trial on track to be initiated in the first half of 2026 – – External PAX-D study published in The Lancet Psychiatry demonstrated a 0.87 effect size for the core mechanism of ALTO-207; this effect represents a significantly larger effect size than current standard-of-care treatments – – ALTO-101 granted FDA Fast Track Designation for CIAS; Topline Phase 2 Proof-of Concept data expected around the end of 1Q 2026 – – Year-end cash balance of $177 million expected to fund planned operations into 2028, covering four key data readouts across Alto's precision psychiatry pip

    3/16/26 6:03:00 AM ET
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    Alto Neuroscience Announces Participation at the Stifel 2026 Virtual CNS Forum

    Alto Neuroscience, Inc. ("Alto") (NYSE:ANRO) a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today announced that members of the Company's management team will participate in a virtual fireside chat at the Stifel 2026 Virtual CNS Forum on March 17, 2026 at 12:00pm ET. The presentation will be accessible via a live webcast on the Events and Presentations page in the Investors section of Alto's website and a replay will be available following the presentation. About Alto Neuroscience Alto Neuroscience is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging neurobi

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    Chardan Capital Markets resumed coverage on Alto Neuroscience with a new price target

    Chardan Capital Markets resumed coverage of Alto Neuroscience with a rating of Buy and set a new price target of $30.00

    1/5/26 9:11:27 AM ET
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    BTIG Research initiated coverage on Alto Neuroscience

    BTIG Research initiated coverage of Alto Neuroscience with a rating of Buy

    11/17/25 9:40:20 AM ET
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    Chardan Capital Markets initiated coverage on Alto Neuroscience with a new price target

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    Alto Neuroscience Reports Second Quarter 2025 Financial Results and Recent Business Highlights

    – Acquisition of potentially best-in-class dopamine agonist combination product candidates, including ALTO-207, expands precision psychiatry pipeline; guided by compelling PAX-D study results published in The Lancet Psychiatry – – ALTO-207 adds expected late-stage readout in treatment resistant depression within current cash runway; planned Phase 2b trial, designed to be a potentially pivotal study expected to initiate by mid-2026 – – Topline data expected from Phase 2 proof-of-concept (POC) trial of ALTO-101 in schizophrenia in the second half of 2025; Phase 2b topline data readouts include ALTO-300 in MDD expected mid-2026 followed by ALTO-100 in bipolar depression expected in the sec

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    Alto Neuroscience Highlights Peer-Reviewed Publication of PAX-D Study in The Lancet Psychiatry Demonstrating Robust Clinical Effects of Pramipexole for Patients with Treatment-Resistant Depression

    –  Compelling PAX-D results guided Alto's acquisition of ALTO-207, designed to induce rapid antidepressant effects while mitigating dose-limiting adverse events of pramipexole – –  Alto plans to collaborate with National Health Service, PAX-D clinical sites for the planned Phase 2b trial of ALTO-207, designed to be a potentially pivotal study; trial expected to initiate by mid-2026 – Alto Neuroscience, Inc. ("Alto") (NYSE:ANRO) a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today highlighted The Lancet Psychiatry publication of data from the PAX-D study evaluating pramipexole in patients with treatment-r

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    Alto Neuroscience Announces Acquisition of Novel Dopamine Agonist Combination Product Candidate, Adding Late-Stage Readout in Treatment Resistant Depression Within Current Cash Runway

    – ALTO-207 (fka CTC-501) is a fixed-dose combination of pramipexole and ondansetron designed to induce rapid antidepressant effects while mitigating dose-limiting adverse events of pramipexole – – Alto has generated proprietary insights on dopamine biomarkers in depression suggesting that direct dopamine receptor activation with ALTO-207 has the potential to be a differentiated therapeutic approach for treatment resistant depression (TRD) – – CTC-501 met primary and secondary endpoints in a completed Phase 2a study in MDD, demonstrating significantly greater improvements on MADRS compared to placebo (Week 8 Cohen's d = 1.1, p<0.05) – – Alto expects to initiate a Phase 2b trial, design

    6/3/25 6:03:00 AM ET
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    Christopher Nixon Cox Named Chairman of High-Trend International Group

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    Alto Neuroscience Appoints Michael Hanley as Chief Operating Officer

    – Mr. Hanley brings over two decades of leadership experience in product development and commercialization across a wide range of neuropsychiatric indications, including major depressive disorder and schizophrenia – Alto Neuroscience, Inc. ("Alto") (NYSE:ANRO) today announced the expansion of the Company's leadership team with the addition of industry veteran Michael Hanley as chief operating officer (COO). Mr. Hanley brings over twenty-five years of leadership experience in the life sciences industry, with established expertise across corporate operations, product development, strategy, and commercialization, with relevant expertise in CNS/neuroscience-focused companies. As Alto's COO, M

    5/21/24 8:05:00 AM ET
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    Amendment: SEC Form SC 13G/A filed by Alto Neuroscience Inc.

    SC 13G/A - Alto Neuroscience, Inc. (0001999480) (Subject)

    11/14/24 5:46:11 PM ET
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    SEC Form SC 13G filed by Alto Neuroscience Inc.

    SC 13G - Alto Neuroscience, Inc. (0001999480) (Subject)

    11/14/24 7:00:29 AM ET
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    SEC Form SC 13G filed by Alto Neuroscience Inc.

    SC 13G - Alto Neuroscience, Inc. (0001999480) (Subject)

    11/12/24 9:50:14 AM ET
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