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    Amendment: SEC Form SC 13G/A filed by BeyondSpring Inc.

    11/14/24 9:52:50 PM ET
    $BYSI
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $BYSI alert in real time by email
    SC 13G/A 1 tm2427620d29_sc13ga.htm SC 13G/A

     

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

    SCHEDULE 13G

     

    Under the Securities Exchange Act of 1934

    (Amendment No. 1)*

     

    BeyondSpring Inc.

    (Name of Issuer)

     

    Ordinary Shares, par value $0.0001 per share

    (Title of Class of Securities)

     

    G10830100

    (CUSIP Number)

     

    September 30, 2024

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨ Rule 13d-1(b)
       
    x Rule 13d-1(c)
       
    ¨ Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital China Life Sciences USD Fund III, L.P.

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,979,073 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,979,073 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,979,073 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    4.9% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    PN

     

    (1)This Schedule 13G is filed by Decheng Capital China Life Sciences USD Fund III, L.P. (“Fund III”), Decheng Capital Management III (Cayman), LLC (“GP III”), Decheng Capital China Life Sciences USD Fund II, L.P. (“Fund II”), Decheng Capital Management II (Cayman), LLC (“GP II”), Decheng Capital Global Healthcare Fund (Master), LP (“Healthcare”), Decheng Capital Global Healthcare GP, LLC (“Healthcare GP”) and Xiangmin Cui (“Dr. Cui” and, with Fund III, GP III, Fund II, GP II, Healthcare and Healthcare GP, collectively, the “Reporting Persons”). The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
       
    (2)Consists of 1,979,073 Ordinary Shares held directly by Fund III. GP III is the general partner of Fund III and Dr. Cui is the sole voting manager of GP III. Fund III, GP III and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund III.
       
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the Securities and Exchange Commission (the “SEC”) on August 29, 2024.

     

    2

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital Management III (Cayman), LLC

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,979,073 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,979,073 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,979,073 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    4.9% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    OO

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
       
    (2)Consists of 1,979,073 Ordinary Shares held directly by Fund III. GP III is the general partner of Fund III and Dr. Cui is the sole voting manager of GP III. Fund III, GP III and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund III.
       
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

    3

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital China Life Sciences USD Fund II, L.P.

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,979,070 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,979,070 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,979,070 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    4.9% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    PN

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
       
    (2)Consists of 1,979,070 Ordinary Shares held directly by Fund II. GP II is the general partner of Fund II and Dr. Cui is the sole voting manager of GP II. Fund II, GP II and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund II.
       
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

    4

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital Management II (Cayman), LLC

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,979,070 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,979,070 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,979,070 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    4.9% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    OO

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
       
    (2)Consists of 1,979,070 Ordinary Shares held directly by Fund II. GP II is the general partner of Fund II and Dr. Cui is the sole voting manager of GP II. Fund II, GP II and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund II.
       
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

     

    5

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital Global Healthcare Fund (Master), LP

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,000,000 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,000,000 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,000,000 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    2.5% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    PN

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
      
    (2)Consists of 1,000,000 Ordinary Shares held directly by Healthcare. Healthcare GP is the general partner of Healthcare and Dr. Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Healthcare, Healthcare GP and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Healthcare.
      
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

    6

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Decheng Capital Global Healthcare GP, LLC

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    1,000,000 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    1,000,000 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,000,000 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    2.5% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    OO

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
      
    (2)Consists of 1,000,000 Ordinary Shares directly by Healthcare. Healthcare GP is the general partner of Healthcare and Dr. Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Healthcare, Healthcare GP and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Healthcare.
      
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

    7

     

     

    CUSIP No.   G10830100
    1.

    Names of Reporting Persons

     

    Xiangmin Cui

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a) ¨ (b) x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

     

    United States

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

     

    0

    6.

    Shared Voting Power

     

    4,958,143 (2)

    7.

    Sole Dispositive Power

     

    0

    8.

    Shared Dispositive Power

     

    4,958,143 (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    4,958,143 (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

     

    12.3% (3)

    12.

    Type of Reporting Person (See Instructions)

     

    IN

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
       
    (2)Consists of (i) 1,979,073 Ordinary Shares held directly by Fund III; (ii) 1,979,070 Ordinary Shares held directly by Fund II; and (iii) 1,000,000 Ordinary Shares held directly by Healthcare. GP III is the general partner of Fund III and Dr. Cui is the sole manager of GP III. Fund III, GP III and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund III. GP II is the general partner of Fund II and Dr. Cui is the sole voting manager of GP II. Fund II, GP II and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund II. Healthcare GP is the general partner of Healthcare and Dr. Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Healthcare, Healthcare GP and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Healthcare.
       
    (3)This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.

     

    8

     

     

    Explanatory Note: This Amendment No. 1 to Schedule 13G amends the Schedule 13G originally filed by Decheng Capital Management III (Cayman), LLC on February 14, 2022.

     

    9

     

     

    Item 1.

     

      (a)

    Name of Issuer

     

    BeyondSpring Inc.

      (b)

    Address of Issuer’s Principal Executive Offices

     

    100 Campus Drive, West Side, 4th Floor, Suite 410, Florham Park, NJ 07932

     

    Item 2.

     

      (a) Name of Person Filing
         
        Decheng Capital China Life Sciences USD Fund III, L.P. (“Fund III”)
        Decheng Capital Management III (Cayman), LLC (“GP III”)
        Decheng Capital China Life Sciences USD Fund II, L.P. (“Fund II”)
        Decheng Capital Management II (Cayman), LLC (“GP II”)
        Decheng Capital Global Healthcare Fund (Master), LP (“Healthcare”)
        Decheng Capital Global Healthcare GP, LLC (“Healthcare GP”)
        Xiangmin Cui (“Dr. Cui”)
      (b) Address of Principal Business Office or, if none, Residence
         
        3000 Sand Hill Road, Building 2, Suite 110, Menlo Park, CA 94025
      (c) Citizenship
         
        Entities: Fund III - Cayman Islands
          GP III - Cayman Islands
          Fund II - Cayman Islands
          GP II - Cayman Islands
          Healthcare - Cayman Islands
          Healthcare GP - Cayman Islands
               
        Individuals: Dr. Cui - United States
      (d) Title of Class of Securities
         
        Ordinary Shares, par value $0.0001 per share (“Ordinary Shares”)
      (e) CUSIP Number
         
        G10830100

     

    Item 3. If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
       
      Not applicable

     

    10

     

     

    Item 4. Ownership

     

    The following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1 is provided as of September 30, 2024:

     

    Reporting
    Persons
      Shares Held
    Directly
        Sole
    Voting
    Power
        Shared
    Voting
    Power
        Sole
    Dispositive
    Power
        Shared
    Dispositive
    Power
        Beneficial
    Ownership
        Percentage
    of Class(4)
     
    Fund III (1)     1,979,073                       1,979,073                        1,979,073       1,979,073       4.9 %
    GP III (1)                     1,979,073               1,979,073       1,979,073       4.9 %
    Fund II (2)     1,979,070               1,979,070               1,979,070       1,979,070       4.9 %
    GP II (2)                     1,979,070               1,979,070       1,979,070       4.9 %
    Healthcare (3)     1,000,000               1,000,000               1,000,000       1,000,000       2.5 %
    Healthcare GP (3)                     1,000,000               1,000,000       1,000,000       2.5 %
    Dr. Cui (1) (2) (3)                     4,958,143               4,958,143       4,958,143       12.3 %

     

    (1) Includes 1,979,073 Ordinary Shares held directly by Fund III. GP III is the general partner of Fund III and Dr. Cui is the sole manager of GP III. Fund III, GP III and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund III.
    (2) Includes 1,979,070 Ordinary Shares held directly by Fund II. GP II is the general partner of Fund II and Dr. Cui is the sole voting manager of GP II. Fund II, GP II and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Fund II.
    (3) Includes 1,000,000 Ordinary Shares held directly by Healthcare. Healthcare GP is the general partner of Healthcare and Dr. Cui is the indirect managing member and ultimate beneficial owner of Healthcare GP. Healthcare, Healthcare GP and Dr. Cui may be deemed to share voting and dispositive power with respect to the shares held directly by Healthcare.
    (4) This calculation is based on 40,300,350 Ordinary Shares outstanding as of June 30, 2024, as reported in the Issuer’s Form 6-K filed with the SEC on August 29, 2024.  

     

    Item 5. Ownership of Five Percent or Less of a Class
       
      If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following   ¨

     

     
    Item 6. Ownership of More than Five Percent on Behalf of Another Person
       
      Not applicable

     

    Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
       
      Not applicable
       
    Item 8. Identification and Classification of Members of the Group
       
      Not applicable

     

    Item 9. Notice of Dissolution of Group
       
      Not applicable

     

    Item 10. Certification
       
      By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

     

    11

     

     

    Signature

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: November 14, 2024

     

    Decheng Capital China Life Sciences USD Fund III, L.P.   Decheng Capital China Life Sciences USD Fund II, L.P.
         
    By its General Partner   By its General Partner
    Decheng Capital Management III (Cayman), LLC   Decheng Capital Management II (Cayman), LLC
         
    By: /s/ Xiangmin Cui   By: /s/ Xiangmin Cui
    Name: Xiangmin Cui   Name: Xiangmin Cui
    Title: Manager   Title: Manager
         
    Decheng Capital Management III (Cayman), LLC   Decheng Capital Management II (Cayman), LLC
         
    By: /s/ Xiangmin Cui   By: /s/ Xiangmin Cui
    Name: Xiangmin Cui   Name: Xiangmin Cui
    Title: Manager   Title: Manager
         
    Decheng Capital Global Healthcare Fund (Master), LP   Decheng Capital Global Healthcare GP, LLC
         
    By its General Partner   By its Manager
    Decheng Capital Global Healthcare GP, LLC   Decheng Capital, LLC
       
    By its Manager   By: /s/ Xiangmin Cui
    Decheng Capital, LLC   Name: Xiangmin Cui
        Title: Manager
    By: /s/ Xiangmin Cui    
    Name: Xiangmin Cui    
    Title: Manager    
         
    /s/ Xiangmin Cui    

     

      ATTENTION  
    Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).

    12

     

     

    Exhibit(s):

     

    AJoint Filing Agreement

     

    13

     

     

    EXHIBIT A

     

    JOINT FILING AGREEMENT

     

    We, the undersigned, hereby express our agreement that the attached Schedule 13G (or any amendments thereto) relating to the Ordinary Shares of BeyondSpring Inc. is filed on behalf of each of us.

     

    Dated: November 14, 2024

     

    Decheng Capital China Life Sciences USD Fund III, L.P.   Decheng Capital China Life Sciences USD Fund II, L.P.
         
    By its General Partner   By its General Partner
    Decheng Capital Management III (Cayman), LLC   Decheng Capital Management II (Cayman), LLC
         
    By: /s/ Xiangmin Cui   By: /s/ Xiangmin Cui
    Name: Xiangmin Cui   Name: Xiangmin Cui
    Title: Manager   Title: Manager
         
    Decheng Capital Management III (Cayman), LLC   Decheng Capital Management II (Cayman), LLC
         
    By: /s/ Xiangmin Cui   By: /s/ Xiangmin Cui
    Name: Xiangmin Cui   Name: Xiangmin Cui
    Title: Manager   Title: Manager
         
    Decheng Capital Global Healthcare Fund (Master), LP   Decheng Capital Global Healthcare GP, LLC
         
    By its General Partner   By its Manager
    Decheng Capital Global Healthcare GP, LLC   Decheng Capital, LLC
       
    By its Manager   By: /s/ Xiangmin Cui
    Decheng Capital, LLC   Name: Xiangmin Cui
        Title: Manager
    By: /s/ Xiangmin Cui    
    Name: Xiangmin Cui    
    Title: Manager    
         
    /s/ Xiangmin Cui    

     

     

     

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    SEC Form 4 filed by Kirkby Matthew

    4 - BeyondSpring Inc. (0001677940) (Issuer)

    4/8/26 4:57:26 PM ET
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    SEC Form 4 filed by Fabbio Patrick

    4 - BeyondSpring Inc. (0001677940) (Issuer)

    4/3/26 5:43:32 PM ET
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    Analyst Ratings

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    BeyondSpring downgraded by Jefferies with a new price target

    Jefferies downgraded BeyondSpring from Buy to Hold and set a new price target of $5.00 from $38.00 previously

    12/2/21 5:17:19 AM ET
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    BeyondSpring downgraded by B of A Securities with a new price target

    B of A Securities downgraded BeyondSpring from Buy to Underperform and set a new price target of $5.00 from $45.00 previously

    12/2/21 4:49:29 AM ET
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    BeyondSpring downgraded by William Blair

    William Blair downgraded BeyondSpring from Outperform to Mkt Perform

    12/1/21 10:55:31 AM ET
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    BeyondSpring Announces Leadership Transition to Deliver Focused Execution on Its Confirmatory DUBLIN-4 Program and Long-Term Value

    Dr. Lan Huang, PhD, remains Chairman of BeyondSpring, committing her time to SEED Therapeutics, where she serves as Co-Founder, Chairman, and Chief Executive Officer — a structure designed to give each company a fully dedicated executive leaderDr. Jiangwen (Jen) Majeti, PhD, MBA, current BeyondSpring Director, appointed Vice Chairman — deepening Board-level governance and providing strategic continuityMin Qiu appointed Chief Executive Officer with a clear mandate: execute DUBLIN-4, extend Plinabulin's scientific optionality, and build BeyondSpring's global partner and investor baseNa Li appointed Chief Financial Officer to strengthen BeyondSpring's financial position and support capital mark

    6/4/26 7:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    BeyondSpring Presents the Latest Update of a Phase 2 Study Demonstrating Durable Clinical Benefit of Pembrolizumab Plus Plinabulin/Docetaxel in Metastatic NSCLC After Progression on First-Line Immune Checkpoint Inhibitor Therapy at ASCO 2026

    Meaningful clinical benefit: Median PFS at 7.0 months, median DoR is 9.3 months with DCR of 79.5% in metastatic NSCLC patients with acquired resistance to immune checkpoint inhibitorsDurable survival benefit: 12-month OS rate of 78.1% and 24-month OS rate of 58.0% in a patient population with limited treatment optionsGood tolerability and immune activation: Along with increased frequencies of activated CD4+/CD8+ T cells post-treatment, hematology test also showed safety benefit with significantly higher levels of WBCs, neutrophils and platelets. FLORHAM PARK, N.J., June 02, 2026 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (NASDAQ:BYSI) ("BeyondSpring" or the "Company"), a clinical-stage company

    6/2/26 7:00:00 AM ET
    $BYSI
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    BeyondSpring Announces Poster Presentation at 2026 ASCO Annual Meeting

    FLORHAM PARK, N.J., May 18, 2026 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (NASDAQ:BYSI) ("BeyondSpring" or the "Company"), a clinical-stage company developing transformative therapies for the treatment of cancer and other diseases, today announced an upcoming poster presentation of Study 303, an investigator-initiated study supported by Merck, known as MSD outside of the United States and Canada, and BeyondSpring, in patients with 2L/3L NSCLC who progressed on PD-1/PD-L1 inhibitors, at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place May 29 through June 2 in Chicago, IL. Presentation details are as follows: Title: A Phase 2 Study of Plinabulin (Plin)/Doceta

    5/18/26 7:00:00 AM ET
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    SEC Filings

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    BeyondSpring Inc. filed SEC Form 8-K: Leadership Update, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - BeyondSpring Inc. (0001677940) (Filer)

    6/4/26 7:30:18 AM ET
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    SEC Form 10-Q filed by BeyondSpring Inc.

    10-Q - BeyondSpring Inc. (0001677940) (Filer)

    5/13/26 4:30:42 PM ET
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    BeyondSpring Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    8-K - BeyondSpring Inc. (0001677940) (Filer)

    5/13/26 7:00:21 AM ET
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    Leadership Updates

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    BeyondSpring Announces Leadership Transition to Deliver Focused Execution on Its Confirmatory DUBLIN-4 Program and Long-Term Value

    Dr. Lan Huang, PhD, remains Chairman of BeyondSpring, committing her time to SEED Therapeutics, where she serves as Co-Founder, Chairman, and Chief Executive Officer — a structure designed to give each company a fully dedicated executive leaderDr. Jiangwen (Jen) Majeti, PhD, MBA, current BeyondSpring Director, appointed Vice Chairman — deepening Board-level governance and providing strategic continuityMin Qiu appointed Chief Executive Officer with a clear mandate: execute DUBLIN-4, extend Plinabulin's scientific optionality, and build BeyondSpring's global partner and investor baseNa Li appointed Chief Financial Officer to strengthen BeyondSpring's financial position and support capital mark

    6/4/26 7:00:00 AM ET
    $BYSI
    Biotechnology: Pharmaceutical Preparations
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    SEED Therapeutics, a BeyondSpring Subsidiary, Appoints Mr. Ko-Yung Tung to the Board of Directors

    NEW YORK, Oct. 23, 2023 (GLOBE NEWSWIRE) -- SEED Therapeutics (SEED), an innovative global biotech company focused on engineering "molecular glues" and harnessing its targeted protein degradation (TPD) platform to attack previously undruggable targets, has appointed eminent international lawyer Ko-Yung Tung to its Board of Directors. SEED is a subsidiary of BeyondSpring (NASDAQ:BYSI), a global clinical-stage biopharmaceutical company developing innovative therapies to improve clinical outcomes for patients with high unmet medical needs. Mr. Tung has served as a director and strategic advisor to leading international corporations and advisory councils, including Eisai Co., Ltd., Hawa

    10/23/23 7:45:00 AM ET
    $BYSI
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    SEED Therapeutics, BeyondSpring Subsidiary, Appoints Jackson Tai to Board of Directors

    Former Director at Eli Lilly, HSBC and MastercardBrings Almost Five Decades of Experience in Finance, Strategy and Risk Governance NEW YORK, June 20, 2023 (GLOBE NEWSWIRE) -- SEED Therapeutics (the "Company"), a BeyondSpring (NASDAQ:BYSI) subsidiary and global research company focused on harnessing and engineering "molecular glues," a targeted protein degradation (TPD) platform to attack previously believed undruggable targets, today announced that it has appointed Jackson Tai to its Board of Directors. Mr. Tai has most recently retired, or will soon retire, as a Non-Executive Director of Eli Lilly (after 10 years), HSBC (after 7 years), and Mastercard (after 15 years). He brings almost 5

    6/20/23 8:00:00 AM ET
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    BeyondSpring Reports First-Quarter 2026 Financial Results and Provides Corporate Update

    AACR 2026 Data Positions Plinabulin as a Potential Backbone Agent to Combine with Antibody-Drug Conjugate (ADC)-Based Therapies to Improve Anti-Cancer Efficacy and Tolerability SEED Advances First Molecular Glue Degrader into Clinical Development with Biomarker-Driven Strategy FLORHAM PARK, N.J., May 13, 2026 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (NASDAQ:BYSI) ("BeyondSpring" or the "Company"), a clinical-stage company developing transformative therapies for the treatment of cancer and other diseases, today announced its financial results for the quarter ended March 31, 2026, and provided a corporate update highlighting significant scientific and clinical advancements across its pipeline

    5/13/26 7:00:00 AM ET
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    BeyondSpring Reports 2025 Year-End Financial Results

    Plinabulin (BeyondSpring's Lead Program): Phase 3 Survival Benefit Confirmed: Plinabulin combined with docetaxel demonstrated statistically significant overall survival benefit vs. standard of care docetaxel in EGFR wild-type NSCLC patients whose tumors progressed after first line therapy — DUBLIN-3 study results published in The Lancet Respiratory Medicine Confirmatory Trial Planned: Based on DUBLIN-3 Phase 3 data and US FDA discussions, BeyondSpring is advancing DUBLIN-4, a confirmatory global Phase 3 study in a biomarker-selected EGFR wild-type NSCLC patient population progressed on immune checkpoint inhibitors (NCT07361484)Overcoming Immunotherapy Resistance: Early clinical data at MD A

    3/25/26 8:30:00 AM ET
    $BYSI
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    BeyondSpring Reports 2024 Year-End Financial Results and Highlights Key Clinical & Strategic Milestones

    Plinabulin Final Phase 3 Data Published in The Lancet Respiratory Medicine, Demonstrating Overall Survival Benefit in 2L/3L NSCLC EGFR Wild Type vs. DocetaxelPlinabulin Phase 2 Data Highlights Potential to Resensitize Tumors Progressed on PD-1/PD-L1 Inhibitors in Metastatic NSCLCSEED Therapeutics Enters into Targeted Protein Degradation Research Collaboration with Eisai with potential payment to SEED of up to $1.5 Billion and Completes $24 Million First Close of Series A-3 FinancingSEED Therapeutics' Lead Oncology Asset RBM39 Degrader Granted Rare Pediatric Disease and Orphan Drug Designations by the FDA FLORHAM PARK, N.J., March 27, 2025 (GLOBE NEWSWIRE) -- BeyondSpring Inc. (NASDAQ:BYSI

    3/27/25 7:00:00 AM ET
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    Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by BeyondSpring Inc.

    SC 13G/A - BeyondSpring Inc. (0001677940) (Subject)

    11/14/24 9:52:50 PM ET
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    SEC Form SC 13G/A filed by BeyondSpring Inc. (Amendment)

    SC 13G/A - BeyondSpring Inc. (0001677940) (Subject)

    2/14/24 4:30:59 PM ET
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    SEC Form SC 13G/A filed by BeyondSpring Inc. (Amendment)

    SC 13G/A - BeyondSpring Inc. (0001677940) (Subject)

    4/7/23 5:02:43 PM ET
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