Turning Point Therapeutics, Inc., a clinical-stage precision oncology biopharmaceutical company, engages in designing and developing therapies that target genetic drivers of cancer. It develops a pipeline of tyrosine kinase inhibitors (TKIs) that targets genetic drivers of cancer in TKI-naïve and TKI-pretreated patients. The company's lead drug candidate repotrectinib is being evaluated in an ongoing Phase 1/2 trial called TRIDENT-1 for the treatment of patients with ROS1+ advanced non-small-cell lung cancer (NSCLC) and patients with ROS1+, NTRK+, or ALK+ advanced solid tumors. Its pipeline also includes multi-targeted drug candidates TPX-0022, a MET/CSF1R/SRC inhibitor, which is in Phase 1 SHIELD-1 clinical trial for patients with advanced solid tumors harboring genetic alterations in MET; TPX-0046, a RET inhibitor that is in Phase 1/2 clinical trial for patients with advanced solid tumors harboring RET genetic alterations; and TPX-0131, a preclinical ALK inhibitor for advanced non-small-cell lung cancer. The company was founded in 2013 and is headquartered in San Diego, California.
IPO Year: 2019
Exchange: NASDAQ
Website: tptherapeutics.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 5/20/2022 | $58.00 | Buy | BofA Securities |
| 3/1/2022 | $50.00 → $45.00 | Hold | Stifel |
| 2/10/2022 | $120.00 → $85.00 | Overweight | Wells Fargo |
| 1/21/2022 | $115.00 → $105.00 | Outperform | Oppenheimer |
| 12/7/2021 | Outperform | Cowen & Co. | |
| 11/10/2021 | $150.00 → $115.00 | Outperform | Oppenheimer |
| 10/12/2021 | $178.00 → $162.00 | Buy | HC Wainwright & Co. |
| 10/11/2021 | Market Outperform → Market Perform | JMP Securities | |
| 9/30/2021 | $75.00 | Hold | Stifel |