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    Summit Therapeutics Inc.

    Subscribe to $SMMT
    $SMMT
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Summit Therapeutics Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat infectious diseases in the United States, Latin America, and Europe. It conducts clinical programs focusing on the Clostridioides difficile infection (CDI). The company's lead product candidate is ridinilazole, an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. It also develops DDS-01 series to treat infection caused by the bacteria Neisseria gonorrhoeae through Discuva platform; and DDS-04 series to treat Enterobacteriaceae. The company was founded in 2003 and is based in Cambridge, Massachusetts.

    IPO Year: 2015

    Exchange: NASDAQ

    Website: summittxinc.com

    Recent Analyst Ratings for Summit Therapeutics Inc.

    DatePrice TargetRatingAnalyst
    6/11/2025$12.00Underperform
    Leerink Partners
    3/26/2025$23.00 → $35.00Neutral → Buy
    Citigroup
    3/21/2025Overweight
    Cantor Fitzgerald
    3/12/2025$30.00Outperform
    Evercore ISI
    2/28/2025$42.00Buy
    Goldman
    1/8/2025$35.00Buy
    Truist
    12/11/2024$30.00Overweight
    Wells Fargo
    12/6/2024$31.00Buy
    Jefferies
    11/4/2024$32.00Mkt Outperform
    JMP Securities
    9/27/2024$19.00 → $23.00Buy → Neutral
    Citigroup
    See more ratings

    Summit Therapeutics Inc. Press Releases

    Fastest customizable press release news feed in the world

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    • Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

      Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced the grant of inducement awards of options to purchase a collective total of up to 71,275 shares of common stock. Awards were made to seven new employees of the Company. The awards were granted as an inducement material to the new employees becoming employees of the Company in accordance with Nasdaq Listing Rule 5635(c)(4) and have been approved by the Company's Compensation Committee. The inducement awards were granted on June 2, 2025. The options have a ten (10) year term and an exercise price of $17.72 per share, the closing price per share of the Company's common stock as reported by Nasdaq on June

      6/6/25 4:44:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics to Participate in the 46th Annual Goldman Sachs Global Healthcare Conference

      Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced that it will participate in and present at the 46th Annual Goldman Sachs Global Healthcare Conference in Miami, Florida on Monday, June 9, 2025, at 1:20 PM ET. Members of the Summit management team will participate in a fireside chat presentation providing a corporate overview and update on the progress of our organization, including the development of our innovative investigational bispecific antibody, ivonescimab. The presentation will be available live from our website: www.smmttx.com. An archived version of the presentation will be available on our website following the presentation. About Summ

      6/5/25 8:00:00 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Ivonescimab Plus Chemotherapy Demonstrates Statistically Significant and Clinically Meaningful Improvement in Progression-Free Survival in Patients with EGFR-Mutant Non-Small Cell Lung Cancer after EGFR TKI Therapy in Global Study

      Consistent Results Noted between Single Region HARMONi-A and Multiregional HARMONi Studies; Favorable Trends in Sub-Populations from North America and China for Both Primary Endpoints Were Observed Ivonescimab in Combination with Chemotherapy Reduces the Risk of Disease Progression or Death by 48% Compared to Chemotherapy Alone; Positive Overall Survival Trend Observed with Hazard Ratio of 0.79 HARMONi Represents the First Phase III Trial to Evaluate Ivonescimab in a Multiregional Setting Summit to Determine Timing of US BLA Filing Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced topline results from the Phase III clinical trial, HARMONi, the

      5/30/25 6:00:00 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

      Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced the grant of inducement awards of options to purchase a collective total of up to 94,050 shares of common stock. Awards were made to nine new employees of the Company. The awards were granted as an inducement material to the new employees becoming employees of the Company in accordance with Nasdaq Listing Rule 5635(c)(4) and have been approved by the Company's Compensation Committee. The inducement awards were granted on May 14, 2025. The options have a ten (10) year term and an exercise price of $22.75 per share, the closing price per share of the Company's common stock as reported by Nasdaq on May 14

      5/16/25 4:30:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Reports Financial Results and Operational Progress for the First Quarter Ended March 31, 2025

      Ivonescimab in Combination with Chemotherapy Achieves Statistically Significant Superiority in PFS vs. Tislelizumab (PD-1 Inhibitor) Plus Chemotherapy in First-Line Treatment of Patients with Advanced Squamous NSCLC in HARMONi-6 Study Conducted by Akeso in China Enrollment Continues in Global Phase III Trial HARMONi-3 in First-Line Treatment of Patients with Metastatic NSCLC Ivonescimab Receives Approval in China as Monotherapy for First-Line Treatment for Advanced NSCLC in Tumors with Positive PD-L1 Expression: Interim Overall Survival HR = 0.777 in China for HARMONi-2 Study Conducted by Akeso Enrollment Has Begun in HARMONi-7 Global Phase III Trial in First-Line PD-L1 High, Metastatic

      5/1/25 4:09:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Interim Overall Survival Analysis Requested from Chinese Health Authorities Shows a Clinically Meaningful, Positive Trend Favoring Ivonescimab Compared to Pembrolizumab in PD-L1 Positive Advanced NSCLC from HARMONi-2 Study Conducted by Akeso in China

      Interim Analysis of HARMONi-2 Shows an Overall Survival Hazard Ratio of 0.777 Favoring Ivonescimab at 39% Data Maturity, Implying a Potential Numerical 22% Reduction in the Risk of Death Compared to Pembrolizumab Ivonescimab Monotherapy Approved by NMPA in China for Front-Line PD-L1 Positive Advanced NSCLC Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today noted that Akeso, Inc. (Akeso, HKEX Code: 9926.HK) announced that ivonescimab was approved by the Chinese Health Authorities, the National Medical Products Administration (NMPA), for a second indication based on the results of the Phase III clinical trial, HARMONi-2 or AK112-303. HARMONi-2 evaluated monother

      4/25/25 2:50:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics to Host First Quarter 2025 Financial Results & Operational Progress Call on May 1, 2025

      Conference Call to be Held at 4:30pm ET Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") will host an earnings call to announce its first quarter 2025 financial results and provide an operational update for the Company on Thursday, May 1, 2025, after the market closes. Summit will host a live webcast of the earnings conference call at 4:30pm ET, which will be accessible through our website, www.smmttx.com. An archived edition of the session will be available on our website. About Summit Therapeutics Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on the discovery, development, and commercialization of patient-, physician-, caregiver- and

      4/24/25 4:15:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Ivonescimab in Combination with Chemotherapy Achieves Statistically Significant Superiority in PFS vs. Tislelizumab (PD-1 Inhibitor) Plus Chemotherapy in 1L Treatment of Patients with Squamous NSCLC in HARMONi-6 Study Conducted by Akeso in China

      Ivonescimab in Combination with Chemotherapy in the HARMONi-6 Study Conducted by Akeso Is the First Known Regimen to Achieve a Clinically Meaningful Benefit over an anti-PD-(L)1 Antibody Combined with Chemotherapy in a Phase III Clinical Trial in 1L NSCLC PFS Improvement Was Observed across Tumors with PD-L1 Negative and PD-L1 Positive Expression in the HARMONi-6 Clinical Trial Conducted by Akeso Full Data Set to be Presented at an Upcoming Major Medical Conference Planned for Later This Year Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today noted that Akeso, Inc. (Akeso, HKEX Code: 9926.HK) announced that the Phase III clinical trial, HARMONi-6 or AK112-306

      4/23/25 6:15:00 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

      Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced the grant of inducement awards of options to purchase a collective total of up to 176,915 shares of common stock. Awards were made to ten (10) new employees of the Company. The awards were granted as an inducement material to the new employees becoming employees of the Company in accordance with Nasdaq Listing Rule 5635(c)(4) and have been approved by the Company's Compensation Committee. The inducement awards were granted on March 31, 2025. The options have a ten (10) year term and an exercise price of $19.29 per share, the closing price per share of the Company's common stock as reported by Nasdaq on

      4/4/25 4:15:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

      Summit Therapeutics Inc. (NASDAQ:SMMT) ("Summit," "we," or the "Company") today announced the grant of inducement awards of options to purchase a collective total of up to 147,500 shares of common stock. Awards were made to seven new employees of the Company. The awards were granted as an inducement material to the new employees becoming employees of the Company in accordance with Nasdaq Listing Rule 5635(c)(4) and have been approved by the Company's Compensation Committee. The inducement awards were granted on March 17, 2025. The options have a ten (10) year term and an exercise price of $20.13 per share, the closing price per share of the Company's common stock as reported by Nasdaq on Ma

      3/21/25 4:15:00 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Summit Therapeutics Inc. Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

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    • Co-Chief Executive Officer Zanganeh Mahkam exercised 74,545 shares at a strike of $2.64 (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      6/2/25 5:01:16 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Co-Chief Executive Officer Duggan Robert W exercised 74,545 shares at a strike of $2.64, increasing direct ownership by 0.01% to 555,754,696 units (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      6/2/25 4:55:56 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Chief Accounting Officer Anand Bhaskar

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      5/1/25 6:17:22 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by COO and CFO Soni Manmeet Singh

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      5/1/25 6:13:55 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Co-Chief Executive Officer Duggan Robert W

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      5/1/25 6:09:55 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Co-Chief Executive Officer Zanganeh Mahkam

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      5/1/25 6:03:44 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Co-Chief Executive Officer Zanganeh Mahkam exercised 3,985,055 in-the-money shares at a strike of $1.58 (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      4/9/25 5:19:31 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Co-Chief Executive Officer Duggan Robert W exercised 3,985,055 in-the-money shares at a strike of $1.58, increasing direct ownership by 0.72% to 555,680,151 units (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      4/9/25 5:12:06 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Chief Accounting Officer Anand Bhaskar

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      1/14/25 4:06:34 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Co-Chief Executive Officer Duggan Robert W

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      1/6/25 7:49:10 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Summit Therapeutics Inc. SEC Filings

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    • Summit Therapeutics Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      6/20/25 5:07:50 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Inc. filed SEC Form 8-K: Submission of Matters to a Vote of Security Holders

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      6/17/25 4:13:55 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      5/30/25 4:17:49 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form S-8 filed by Summit Therapeutics Inc.

      S-8 - Summit Therapeutics Inc. (0001599298) (Filer)

      5/19/25 4:45:32 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Summit Therapeutics Inc.

      10-Q - Summit Therapeutics Inc. (0001599298) (Filer)

      5/1/25 4:11:31 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      5/1/25 4:10:10 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEF 14A filed by Summit Therapeutics Inc.

      DEF 14A - Summit Therapeutics Inc. (0001599298) (Filer)

      4/29/25 4:44:20 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      4/25/25 4:38:11 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K - Summit Therapeutics Inc. (0001599298) (Filer)

      4/23/25 8:54:14 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-K filed by Summit Therapeutics Inc.

      10-K - Summit Therapeutics Inc. (0001599298) (Filer)

      2/24/25 6:53:28 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Summit Therapeutics Inc. Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Zanganeh Mahkam bought $411,094 worth of shares (110,321 units at $3.73), increasing direct ownership by 5% to 520,814 units (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      3/27/24 8:28:30 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Dhingra Ankur bought $375,000 worth of shares (100,000 units at $3.75) (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      3/27/24 8:27:03 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Zanganeh Mahkam exercised 805,495 in-the-money shares at a strike of $1.49 and bought $10,350 worth of shares (5,000 units at $2.07) (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      12/13/23 5:11:56 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Dhingra Ankur bought $44,254 worth of shares (20,400 units at $2.17) (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      12/13/23 4:49:19 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Soni Manmeet Singh bought $4,999,999 worth of shares (2,976,190 units at $1.68) (SEC Form 4)

      4 - Summit Therapeutics Inc. (0001599298) (Issuer)

      10/16/23 4:06:32 PM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Summit Therapeutics Inc. Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Leerink Partners initiated coverage on Summit Therapeutics with a new price target

      Leerink Partners initiated coverage of Summit Therapeutics with a rating of Underperform and set a new price target of $12.00

      6/11/25 7:54:51 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics upgraded by Citigroup with a new price target

      Citigroup upgraded Summit Therapeutics from Neutral to Buy and set a new price target of $35.00 from $23.00 previously

      3/26/25 7:47:33 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Cantor Fitzgerald initiated coverage on Summit Therapeutics

      Cantor Fitzgerald initiated coverage of Summit Therapeutics with a rating of Overweight

      3/21/25 8:11:46 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Evercore ISI initiated coverage on Summit Therapeutics with a new price target

      Evercore ISI initiated coverage of Summit Therapeutics with a rating of Outperform and set a new price target of $30.00

      3/12/25 7:33:36 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Goldman initiated coverage on Summit Therapeutics with a new price target

      Goldman initiated coverage of Summit Therapeutics with a rating of Buy and set a new price target of $42.00

      2/28/25 7:33:16 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Truist initiated coverage on Summit Therapeutics with a new price target

      Truist initiated coverage of Summit Therapeutics with a rating of Buy and set a new price target of $35.00

      1/8/25 8:30:04 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Wells Fargo initiated coverage on Summit Therapeutics with a new price target

      Wells Fargo initiated coverage of Summit Therapeutics with a rating of Overweight and set a new price target of $30.00

      12/11/24 8:25:16 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Jefferies initiated coverage on Summit Therapeutics with a new price target

      Jefferies initiated coverage of Summit Therapeutics with a rating of Buy and set a new price target of $31.00

      12/6/24 8:15:54 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • JMP Securities initiated coverage on Summit Therapeutics with a new price target

      JMP Securities initiated coverage of Summit Therapeutics with a rating of Mkt Outperform and set a new price target of $32.00

      11/4/24 7:40:20 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Summit Therapeutics downgraded by Citigroup with a new price target

      Citigroup downgraded Summit Therapeutics from Buy to Neutral and set a new price target of $23.00 from $19.00 previously

      9/27/24 7:42:54 AM ET
      $SMMT
      Biotechnology: Pharmaceutical Preparations
      Health Care