Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing PRX002/RG7935 that is in Phase 2 clinical trial for treating Parkinson's disease and other related synucleinopathies; and PRX004, an antibody that is in Phase 1 clinical trial for the treatment of ATTR amyloidosis. Its discovery-stage programs include Tau for treating Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, chronic traumatic encephalopathy, and other tauopathies; AÃ, or Amyloid Beta, a protein for the treatment of Alzheimer's disease; TDP-43 for amyotrophic lateral sclerosis and frontotemporal dementia; and other products for neurodegenerative diseases. The company has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. Prothena Corporation plc was founded in 2012 and is based in Dublin, Ireland.
IPO Year:
Exchange: NASDAQ
Website: prothena.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 5/28/2025 | $4.00 | Neutral → Underperform | BofA Securities |
| 5/27/2025 | Outperform → Perform | Oppenheimer | |
| 5/27/2025 | $6.00 | Buy → Hold | Jefferies |
| 5/27/2025 | Overweight → Neutral | Cantor Fitzgerald | |
| 12/20/2024 | $40.00 | Buy | Chardan Capital Markets |
| 1/30/2024 | $68.00 → $38.00 | Buy → Neutral | BofA Securities |
| 12/12/2023 | $62.00 | Buy | Deutsche Bank |
| 4/24/2023 | $80.00 | Outperform | SVB Securities |
| 1/27/2023 | $94.00 | Overweight | Piper Sandler |
| 11/4/2022 | $52.00 → $55.00 | Outperform → Sector Perform | RBC Capital Mkts |