Calithera Biosciences, Inc., a clinical-stage bio-pharmaceutical company, focuses on the discovery and development of small molecule drugs directed against tumor metabolism and tumor immunology targets for the treatment of cancer in the United States. Its lead product candidate is CB-839, an inhibitor of glutaminase, which is in Phase II clinical trial to treat solid tumors. The company also offers INCB001158, an oral inhibitor of arginase that is in Phase I/II clinical trial for the treatment of hematology and oncology. The company is also developing CB-280, an oral arginase inhibitor that is in Phase 1b clinical trial for the treatment of cystic fibrosis and chronic airway infection; and CB-708, an orally administered small molecule inhibitor of CD73, as well as CB-668, an inhibitor of the enzyme IL4I1. It has a license agreement with Mars, Inc. to develop and commercialize Symbioscience's portfolio of arginase inhibitors for use in human healthcare. The company also has clinical trial collaboration with Pfizer to evaluate Pfizer's PARP inhibitor talazoparib and CDK4/6 inhibitor palbociclib, each in combination with telaglenasta. In addition, it has a collaboration and license agreement with Incyte Corporation for the research, development, and commercialization of INCB001158, a small molecule arginase inhibitor for the treatment of hematology and oncology; and a license agreement with Antengene Corporation Ltd. for the development and commercialization of CB-708. Calithera Biosciences, Inc. was incorporated in 2010 and is headquartered in South San Francisco, California.
IPO Year: 2014
Exchange: NASDAQ
Website: calithera.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 1/31/2022 | $4.00 | Buy | Ladenburg Thalmann |
| 1/20/2022 | $1.00 → $3.00 | Market Perform → Outperform | SVB Leerink |
| 11/8/2021 | Buy → Neutral | HC Wainwright & Co. | |
| 11/5/2021 | Outperform → Market Perform | William Blair |
Ladenburg Thalmann initiated coverage of Calithera Biosciences with a rating of Buy and set a new price target of $4.00
SVB Leerink upgraded Calithera Biosciences from Market Perform to Outperform and set a new price target of $3.00 from $1.00 previously
HC Wainwright & Co. downgraded Calithera Biosciences from Buy to Neutral
William Blair downgraded Calithera Biosciences from Outperform to Market Perform
DEFM14A - Calithera Biosciences, Inc. (0001496671) (Filer)
PREM14A - Calithera Biosciences, Inc. (0001496671) (Filer)
DEFA14A - Calithera Biosciences, Inc. (0001496671) (Filer)
EFFECT - Calithera Biosciences, Inc. (0001496671) (Filer)
15-12G - Calithera Biosciences, Inc. (0001496671) (Filer)
S-8 POS - Calithera Biosciences, Inc. (0001496671) (Filer)
S-8 POS - Calithera Biosciences, Inc. (0001496671) (Filer)
S-8 POS - Calithera Biosciences, Inc. (0001496671) (Filer)
S-8 POS - Calithera Biosciences, Inc. (0001496671) (Filer)
S-8 POS - Calithera Biosciences, Inc. (0001496671) (Filer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
4 - Calithera Biosciences, Inc. (0001496671) (Issuer)
SOUTH SAN FRANCISCO, Calif., Dec. 31, 2020 (GLOBE NEWSWIRE) -- Calithera Biosciences, Inc. (Nasdaq: CALA), a clinical stage biotechnology company focused on discovering and developing novel small molecule drugs for the treatment of cancer and other life-threatening diseases, today announced that the compensation committee of the company’s board of directors granted one new employee a non-qualified stock option to purchase an aggregate of 50,000 shares of Calithera’s common stock, at a per share exercise price of $4.91, the closing trading price on December 31, 2020. One-fourth of the option vests in December 2021, and the balance of the option vests in a series of thirty-six successive equ