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    Pyxis Oncology Inc.

    Subscribe to $PYXS
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology, Inc., a preclinical stage biotechnology company, engages in the development of antibody-drug conjugates (ADCs) and monoclonal antibody (mAb) immunotherapies to treat cancers. Its preclinical products pipeline includes PYX-201, a site-specific investigational ADC targeting onco-fetal fibronectin extradomain-B for the treatment of non-small cell lung cancer; PYX-202, a site-specific investigational ADC targeting delta like non-canonical notch ligand 1 to treat small cell lung cancer, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational site-specific ADC targeting CD123 for the treatment of acute myeloid leukemia and other blood cancers. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

    IPO Year: 2021

    Exchange: NASDAQ

    Website: pyxisoncology.com

    Peers

    $PXS

    Recent Analyst Ratings for Pyxis Oncology Inc.

    DatePrice TargetRatingAnalyst
    5/5/2026$6.00Outperform
    Wedbush
    11/3/2025$9.00Buy
    Stifel
    9/4/2025$5.00Buy
    Guggenheim
    11/21/2024Outperform → Mkt Perform
    William Blair
    11/8/2024$13.00Overweight
    Stephens
    8/8/2024$10.00Buy
    Stifel
    5/7/2024$10.00Buy
    Jefferies
    2/9/2024$8.00Buy
    BTIG Research
    1/23/2024$12.00Outperform
    Leerink Partners
    9/5/2023$7.00Outperform
    RBC Capital Mkts
    See more ratings

    Pyxis Oncology Inc. Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    Wedbush initiated coverage on Pyxis Oncology with a new price target

    Wedbush initiated coverage of Pyxis Oncology with a rating of Outperform and set a new price target of $6.00

    5/5/26 7:44:12 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Stifel resumed coverage on Pyxis Oncology with a new price target

    Stifel resumed coverage of Pyxis Oncology with a rating of Buy and set a new price target of $9.00

    11/3/25 9:08:29 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Guggenheim initiated coverage on Pyxis Oncology with a new price target

    Guggenheim initiated coverage of Pyxis Oncology with a rating of Buy and set a new price target of $5.00

    9/4/25 9:07:21 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology downgraded by William Blair

    William Blair downgraded Pyxis Oncology from Outperform to Mkt Perform

    11/21/24 7:55:42 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Stephens initiated coverage on Pyxis Oncology with a new price target

    Stephens initiated coverage of Pyxis Oncology with a rating of Overweight and set a new price target of $13.00

    11/8/24 8:24:38 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Stifel initiated coverage on Pyxis Oncology with a new price target

    Stifel initiated coverage of Pyxis Oncology with a rating of Buy and set a new price target of $10.00

    8/8/24 6:48:55 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Jefferies resumed coverage on Pyxis Oncology with a new price target

    Jefferies resumed coverage of Pyxis Oncology with a rating of Buy and set a new price target of $10.00

    5/7/24 7:46:16 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    BTIG Research initiated coverage on Pyxis Oncology with a new price target

    BTIG Research initiated coverage of Pyxis Oncology with a rating of Buy and set a new price target of $8.00

    2/9/24 6:20:24 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Leerink Partners initiated coverage on Pyxis Oncology with a new price target

    Leerink Partners initiated coverage of Pyxis Oncology with a rating of Outperform and set a new price target of $12.00

    1/23/24 8:08:22 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    RBC Capital Mkts initiated coverage on Pyxis Oncology with a new price target

    RBC Capital Mkts initiated coverage of Pyxis Oncology with a rating of Outperform and set a new price target of $7.00

    9/5/23 7:17:04 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    CFO & COO Connealy Pamela Ann bought $174,364 worth of shares (88,850 units at $1.96) (SEC Form 4)

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    11/27/24 5:09:59 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Connealy Pamela Ann bought $14,960 worth of shares (8,000 units at $1.87), increasing direct ownership by 0.99% to 818,532 units (SEC Form 4)

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/28/23 4:32:03 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Wadhane Jitendra bought $4,675 worth of shares (2,500 units at $1.87), increasing direct ownership by 1% to 226,937 units (SEC Form 4)

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/27/23 6:37:45 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Connealy Pamela Ann bought $11,868 worth of shares (6,426 units at $1.85), increasing direct ownership by 0.80% to 810,532 units (SEC Form 4)

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/27/23 6:36:38 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Wadhane Jitendra bought $8,850 worth of shares (5,000 units at $1.77), increasing direct ownership by 2% to 224,437 units

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/25/23 5:05:30 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Connealy Pamela Ann bought $20,044 worth of shares (12,000 units at $1.67), increasing direct ownership by 2% to 804,106 units

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/25/23 5:04:12 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Wadhane Jitendra bought $4,349 worth of shares (2,500 units at $1.74), increasing direct ownership by 1% to 219,437 units

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/22/23 7:35:51 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Connealy Pamela Ann bought $8,695 worth of shares (5,000 units at $1.74), increasing direct ownership by 0.64% to 792,106 units

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    9/22/23 7:34:33 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. Press Releases

    Fastest customizable press release news feed in the world

    View All

    Pyxis Oncology Reports First Quarter 2026 Financial Results and Advances MICVO Toward Key 2026 Clinical Milestones

    Updated micvotabart pelidotin (MICVO) Phase 1 monotherapy data in 2L+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) on track for mid-year 2026; update to include analyses focused on patients treated at or below a dose cap Completed target enrollment in Phase 1 monotherapy dose expansion study of MICVO in 2L+ R/M HNSCC in the first quarter of 2026 Updated data from MICVO Phase 1/2 dose escalation study in combination with pembrolizumab in 1L R/M HNSCC on track for the second half of 2026 Presented new preclinical data at the American Association for Cancer Research (AACR) Annual Meeting 2026 that support the clinical development of MICVO as both a monotherapy

    5/14/26 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology to Participate in Upcoming Investor Conferences

    BOSTON, May 13, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that management will participate in the following upcoming investor conferences: RBC Capital Markets Global Healthcare Conference in New York, NY on Tuesday, May 19, 2026, fireside chat at 2:35 p.m. ET; andStifel Virtual Oncology Forum on Wednesday, May 20, 2026, fireside chat at 3:30 p.m. ET; andJefferies Global Healthcare Conference in New York, NY on Thursday, June 4, 2026, fireside chat at 7:35 a.m. ET. Live webcasts and replays of the fireside chats will be available on the Events & Presentations

    5/13/26 7:30:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Appoints Nelson Azoulay as Chief Business Officer

    BOSTON, May 07, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced the appointment of Nelson Azoulay as Chief Business Officer. Mr. Azoulay joins Pyxis Oncology with more than 15 years of experience in corporate strategy, business development, and value-creating transactions across the biopharma industry, including deep antibody-drug conjugate (ADC) experience. In his role, he will lead corporate development strategy and pursue strategic opportunities to advance MICVO, the Company's lead clinical asset. "We're excited to welcome Nelson to Pyxis Oncology," said Tom Ci

    5/7/26 4:05:00 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology to Present New Preclinical Data Showing Synergistic Anti-Tumor Activity in a HNSCC model with maMICVO in Combination with Anti-PD-1 at AACR 2026

    Mouse analog of MICVO (maMICVO) monotherapy produced dose-dependent inhibition of tumor growth in a syngeneic preclinical model of HNSCC maMICVO monotherapy modulated the tumor-immune environment in a syngeneic preclinical model of HNSCC toward a more favorable immune-permissive environment for immunotherapy maMICVO in combination with anti-mouse PD-1 worked synergistically to produce greater anti-tumor activity compared with either treatment alone in an immune-refractory syngeneic preclinical model of HNSCC Preclinical findings support the ongoing clinical development of MICVO as both monotherapy and in combination with pembrolizumab for R/M HNSCC BOSTON, April 17, 2026 (GLOBE NEWSWIR

    4/17/26 4:05:00 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Provides Business Update and Reports Fourth Quarter and Full Year 2025 Financial Results

    Completed target enrollment in Phase 1 monotherapy dose expansion study of micvotabart pelidotin (MICVO) in 2L+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) in the first quarter of 2026 Updated data from MICVO Phase 1 monotherapy study in 2L+ R/M HNSCC on track for mid-year 2026; to include patients treated with modified weight-based dosing and patients treated with total body weight dosing Updated data from MICVO Phase 1/2 dose escalation study in combination with KEYTRUDA® in 1L/2L+ R/M HNSCC on track for the second half of 2026 Announced appointment of Thomas Civik as Interim Chief Executive Officer Expected cash runway into the fourth quarter of 2026 BOSTO

    3/23/26 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Announces Interim CEO Appointment and Leadership Transition to Support Strategic Focus and Program Continuity

    BOSTON, Feb. 03, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced a leadership transition to continue execution and advancement of the Company's strategic and clinical goals. Thomas Civik, a member of Pyxis Oncology's Board of Directors since the Company's IPO and a highly experienced biotechnology executive with a proven track record in advancing cancer therapeutics, has been appointed Interim Chief Executive Officer, effective immediately. Lara S. Sullivan, M.D., has stepped down from her roles as President, Chief Executive Officer and Chief Medical Officer. With

    2/3/26 6:45:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    The $225B Precision Sprint: How Big Pharma is Beating the $170B Patent Cliff

    VANCOUVER, British Columbia, Jan. 12, 2026 (GLOBE NEWSWIRE) -- Equity-Insider.com News Commentary – The biotechnology sector is entering a high-stakes survival sprint as major pharmaceutical giants confront a looming $170 billion patent cliff[1]. This massive pressure is forcing a strategic capital rotation toward late-stage, registration-ready oncology platforms that can be delivered with biologic-like manufacturing efficiency. With blockbuster drugs losing exclusivity through 2030, the precision oncology market is projected to reach $225.65 billion by 2032[2] as buyers aggressively target scalable technologies. This industry-wide shift into proprietary precision platforms fuels the 2026

    1/12/26 10:14:09 AM ET
    $ALLO
    $CHRS
    $ELVN
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    Pyxis Oncology Announces Positive Preliminary Phase 1 Data for Micvotabart Pelidotin (MICVO) in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

    46% confirmed objective response rate (ORR) and 92% disease control rate (DCR) observed with MICVO as monotherapy in 2L+ R/M HNSCC at 5.4 mg/kg 71% confirmed ORR and 100% DCR observed with MICVO in combination with KEYTRUDA® (pembrolizumab) in 1L/2L+ R/M HNSCC at 3.6 mg/kg and 4.4 mg/kgUpdated data from ongoing Phase 1 monotherapy study in 2L+ R/M HNSCC expected mid-2026; updated data from ongoing Phase 1/2 study evaluating MICVO in combination with KEYTRUDA®, including in 1L/2L+ R/M HNSCC and other tumor types, expected 2H26 Company to host webcast and conference call today at 8:30 a.m. ET BOSTON, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage comp

    12/18/25 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology to Participate in Upcoming Investor Conferences

    BOSTON, Nov. 03, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that management will participate in the following upcoming investor conferences in November 2025: Guggenheim 2nd Annual Healthcare Innovation Conference, Boston, MA, Monday, November 10, 2:30 p.m. ET. – Fireside chat.Stifel 2025 Healthcare Conference, New York, NY, Tuesday, November 11, 4:00 p.m. ET. – Fireside chat. Live webcasts and replays of the Guggenheim and Stifel fireside chats will be available on the Events & Presentations page in the Investor Relations section of Pyxis Oncology's website,

    11/3/25 4:05:00 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Provides Business Update and Reports Third Quarter 2025 Financial Results

    -  Preliminary data from ongoing Phase 1 clinical studies of micvotabart pelidotin (MICVO) in patients with recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC) expected in the fourth quarter of 2025 -  Clinical update to focus on preliminary data from Phase 1 monotherapy dose expansion study of MICVO in 2L/3L R/M HNSCC patients, including from both post platinum & PD-1 and post EGFR & PD-1 arms, and preliminary data from Phase 1/2 combination dose escalation study of MICVO and KEYTRUDA® (pembrolizumab) in 1L/2L+ R/M HNSCC patients -  Presented translational data at ESMO 2025 and AACR-NCI-EORTC providing meaningful insights into MICVO's first-in-concept non-cellul

    11/3/25 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. SEC Filings

    View All

    SEC Form 10-Q filed by Pyxis Oncology Inc.

    10-Q - Pyxis Oncology, Inc. (0001782223) (Filer)

    5/14/26 7:56:16 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    8-K - Pyxis Oncology, Inc. (0001782223) (Filer)

    5/14/26 7:36:49 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEFA14A filed by Pyxis Oncology Inc.

    DEFA14A - Pyxis Oncology, Inc. (0001782223) (Filer)

    4/30/26 7:40:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEF 14A filed by Pyxis Oncology Inc.

    DEF 14A - Pyxis Oncology, Inc. (0001782223) (Filer)

    4/30/26 7:35:52 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: Pyxis Oncology Inc. filed SEC Form 8-K: Leadership Update

    8-K/A - Pyxis Oncology, Inc. (0001782223) (Filer)

    4/30/26 7:04:36 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form S-8 filed by Pyxis Oncology Inc.

    S-8 - Pyxis Oncology, Inc. (0001782223) (Filer)

    3/23/26 4:05:06 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 10-K filed by Pyxis Oncology Inc.

    10-K - Pyxis Oncology, Inc. (0001782223) (Filer)

    3/23/26 7:17:26 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - Pyxis Oncology, Inc. (0001782223) (Filer)

    3/23/26 7:12:28 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SCHEDULE 13G/A filed by Pyxis Oncology Inc.

    SCHEDULE 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    2/9/26 11:23:13 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. filed SEC Form 8-K: Leadership Update, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - Pyxis Oncology, Inc. (0001782223) (Filer)

    2/6/26 4:07:28 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by Dupont Jakob

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:18:44 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Wadhane Jitendra

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:17:26 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Flavin John L

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:10:59 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Metzger Michael A

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:09:52 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Lewis-Hall Freda C

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:08:25 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Cline Darren S

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:07:11 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Humphrey Rachel

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:05:57 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Palani Santhosh

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 5:04:44 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Humphrey Rachel

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    3/25/26 4:30:11 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Interim CEO Civik Thomas

    4 - Pyxis Oncology, Inc. (0001782223) (Issuer)

    2/5/26 8:37:38 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Inc. Leadership Updates

    Live Leadership Updates

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    Pyxis Oncology Reports First Quarter 2026 Financial Results and Advances MICVO Toward Key 2026 Clinical Milestones

    Updated micvotabart pelidotin (MICVO) Phase 1 monotherapy data in 2L+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) on track for mid-year 2026; update to include analyses focused on patients treated at or below a dose cap Completed target enrollment in Phase 1 monotherapy dose expansion study of MICVO in 2L+ R/M HNSCC in the first quarter of 2026 Updated data from MICVO Phase 1/2 dose escalation study in combination with pembrolizumab in 1L R/M HNSCC on track for the second half of 2026 Presented new preclinical data at the American Association for Cancer Research (AACR) Annual Meeting 2026 that support the clinical development of MICVO as both a monotherapy

    5/14/26 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Appoints Nelson Azoulay as Chief Business Officer

    BOSTON, May 07, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced the appointment of Nelson Azoulay as Chief Business Officer. Mr. Azoulay joins Pyxis Oncology with more than 15 years of experience in corporate strategy, business development, and value-creating transactions across the biopharma industry, including deep antibody-drug conjugate (ADC) experience. In his role, he will lead corporate development strategy and pursue strategic opportunities to advance MICVO, the Company's lead clinical asset. "We're excited to welcome Nelson to Pyxis Oncology," said Tom Ci

    5/7/26 4:05:00 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Provides Business Update and Reports Fourth Quarter and Full Year 2025 Financial Results

    Completed target enrollment in Phase 1 monotherapy dose expansion study of micvotabart pelidotin (MICVO) in 2L+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) in the first quarter of 2026 Updated data from MICVO Phase 1 monotherapy study in 2L+ R/M HNSCC on track for mid-year 2026; to include patients treated with modified weight-based dosing and patients treated with total body weight dosing Updated data from MICVO Phase 1/2 dose escalation study in combination with KEYTRUDA® in 1L/2L+ R/M HNSCC on track for the second half of 2026 Announced appointment of Thomas Civik as Interim Chief Executive Officer Expected cash runway into the fourth quarter of 2026 BOSTO

    3/23/26 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Announces Interim CEO Appointment and Leadership Transition to Support Strategic Focus and Program Continuity

    BOSTON, Feb. 03, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced a leadership transition to continue execution and advancement of the Company's strategic and clinical goals. Thomas Civik, a member of Pyxis Oncology's Board of Directors since the Company's IPO and a highly experienced biotechnology executive with a proven track record in advancing cancer therapeutics, has been appointed Interim Chief Executive Officer, effective immediately. Lara S. Sullivan, M.D., has stepped down from her roles as President, Chief Executive Officer and Chief Medical Officer. With

    2/3/26 6:45:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Appoints Alex Kane as Senior Vice President, Investor Relations & Capital Markets

    BOSTON, Oct. 09, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company developing antibody-drug conjugate (ADC) therapeutics for difficult-to-treat cancers, today announced the appointment of Alex Kane, MBA, as Senior Vice President, Investor Relations & Capital Markets, effective immediately. Mr. Kane brings 20 years of experience and a proven track record in investor relations, strategic communications, and equity capital markets across the life sciences sector. He joins Pyxis Oncology from Guggenheim Securities, where he served as Vice President of Equity Capital Markets, advising biotechnology clients on financing strategies and equity transactions. Pr

    10/9/25 7:30:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Expands Board of Directors with Appointment of Michael A. Metzger

    BOSTON, June 10, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: "PYXS"), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today announced the appointment of Michael A. Metzger to its Board of Directors, effective June 10, 2024. Mr. Metzger has over 25 years of experience in the biopharmaceutical sector, currently serving as Chief Executive Officer and as a member of the Board of Directors of Syndax Pharmaceuticals, Inc. (NASDAQ:SNDX) since 2015. "We are delighted to have Michael, a proven leader in our industry with a robust track record of success, join the board," said Lara S. Sullivan, M.D., President and Chief Ex

    6/10/24 7:30:00 AM ET
    $PYXS
    $SNDX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pyxis Oncology Expands Board of Directors with Appointment of Santhosh Palani, Ph.D., CFA

    BOSTON, March 13, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: "PYXS"), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today announced the appointment of Santhosh Palani, Ph.D., CFA, to its board of directors, effective March 12, 2024. "We are thrilled to have Santhosh join the Pyxis Oncology board. Santhosh brings a wealth of business, investment, strategic, and board experience to our team," said Lara S. Sullivan, M.D., President and Chief Executive Officer of Pyxis Oncology. "Santhosh's guidance, drawing from his experience working across the biopharma industry, will be invaluable as we continue clinical devel

    3/13/24 8:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    1910 Genetics Appoints Dr. Shaan C. Gandhi as Independent Board Director

    Dr. Gandhi is VP and Head of Strategic Partnerships for Pfizer Ignite and will bring clinical, strategic and financial leadership to biotech's board 1910 Genetics, the only biotech advancing small and large molecule drug discovery with an automated, multimodal AI platform, today announced the appointment of Shaan C. Gandhi, MD, DPhil, to its board of directors. Gandhi joins as an independent board director and will provide a critical clinical perspective alongside his extensive background in biotechnology investing and strategic collaboration at a time when 1910 Genetics continues to build pharmaceutical and technology partnerships and advance its own pipeline of AI-derived therapeutics.

    12/19/23 9:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology Announces Appointment of Ken Kobayashi, M.D., F.A.C.P as Chief Medical Officer

    BOSTON, Nov. 28, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company focused on developing next-generation therapeutics to target difficult-to-treat cancers, today announced the appointment of Ken Kobayashi, M.D., F.A.C.P, as Chief Medical Officer (CMO), effective November 27, 2023. Dr. Kobayashi brings extensive leadership experience in oncology clinical development and regulatory affairs. As CMO, Dr. Kobayashi will lead the Company's clinical and regulatory operations, drive strategic growth, and play a key role in advancing Pyxis Oncology's clinical pipeline. "I am thrilled to welcome Ken to the Pyxis Oncology team, and I look forward to working closel

    11/28/23 7:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology Announces Leadership Changes

    - Ronald Herbst, Ph.D., stepping down as Chief Scientific Officer - - Jan Pinkas, Ph.D., promoted to Chief Scientific Officer - - Company continues to advance programs toward the clinic with IND filings for Anti-EDB, PYX-201, and Anti-Siglec-15, PYX-106, expected in 2H22 - CAMBRIDGE, Mass., April 13, 2022 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS) today announced the departure of Ronald Herbst, Ph.D., as the Company's Chief Scientific Officer and the appointment of Jan Pinkas, Ph.D., currently Senior Vice President, Preclinical Research & Development, to the position of Chief Scientific Officer. The management changes are effective as of April 12, 2022. "Ronald's passion, e

    4/13/22 6:35:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology Inc. Financials

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    Pyxis Oncology Announces Positive Preliminary Phase 1 Data for Micvotabart Pelidotin (MICVO) in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

    46% confirmed objective response rate (ORR) and 92% disease control rate (DCR) observed with MICVO as monotherapy in 2L+ R/M HNSCC at 5.4 mg/kg 71% confirmed ORR and 100% DCR observed with MICVO in combination with KEYTRUDA® (pembrolizumab) in 1L/2L+ R/M HNSCC at 3.6 mg/kg and 4.4 mg/kgUpdated data from ongoing Phase 1 monotherapy study in 2L+ R/M HNSCC expected mid-2026; updated data from ongoing Phase 1/2 study evaluating MICVO in combination with KEYTRUDA®, including in 1L/2L+ R/M HNSCC and other tumor types, expected 2H26 Company to host webcast and conference call today at 8:30 a.m. ET BOSTON, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage comp

    12/18/25 7:00:00 AM ET
    $PYXS
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    Pyxis Oncology Provides Corporate Update and Reports Financial Results for Third Quarter 2024

    - Preliminary data from the first-in-patient Phase 1 dose escalation trial of PYX-201 to be announced at upcoming virtual and in-person event in New York City on Wednesday, November 20, 2024, at 4:30 p.m. ET - Preliminary data from the Phase 1 trial of PYX-106 is expected to be reported by year-end 2024 - Expected cash runway into 2H 2026 BOSTON, Mass., Nov. 12, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today reported financial results for the third quarter ended September 30, 2024, and provided a corporate update. The Company ended the third quarter of 20

    11/12/24 7:30:00 AM ET
    $PYXS
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    Pyxis Oncology Provides Corporate Update and Reports Financial Results for Second Quarter 2024

    - Preliminary data from the Phase 1 trial of PYX-201 remains on track to be announced in the fall of 2024 - Preliminary data from the Phase 1 trial of PYX-106 is expected to be reported by year-end 2024 - Expected cash runway into 2H 2026 BOSTON, Aug. 14, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today reported financial results for the second quarter ended June 30, 2024, and provided a corporate update. The Company ended the second quarter of 2024 with $157.2 million in cash, cash equivalents, restricted cash and short-term investments, which is expected

    8/14/24 4:05:00 PM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology Provides Corporate Update and Reports Financial Results for First Quarter 2024

    PYX-201 Phase 1 trial clinical readout on track for fall of 2024 Executive Leadership Team expanded with the appointment of Stephen Worsley as Senior Vice President, Chief Business Officer PYX-106 Phase 1 trial clinical readout on track for 2H 2024 Expected cash runway into 2H 2026 BOSTON, May 14, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today reported financial results for the first quarter ended March 31, 2024, and provided a corporate update. PYX-201, a first-in-concept tumor stroma targeting antibody-drug conjugate (ADC) against the stromal Extradom

    5/14/24 7:30:00 AM ET
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    Pyxis Oncology Provides Corporate Update and Reports Financial Results for Fourth Quarter and Full Year 2023

    PYX-201 Phase 1 Part 1 trial progressing with initial data expected in the fall of 2024 PYX-106 Phase 1 trial progressing with initial data expected 2H 2024 Completed $50 million private placement Expected cash runway into 2H 2026 BOSTON, March 21, 2024 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical stage company focused on developing next generation therapeutics to target difficult-to-treat cancers, today reported financial results for the year and quarter ended December 31, 2023, and provided a corporate update. PYX-201, a first-in-concept tumor stroma targeting antibody-drug conjugate (ADC) against the stromal Extradomain-B Fibrone

    3/21/24 7:30:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology Announces Initiatives to Prioritize Lead ADC Program; Reports Financial Results for Third-Quarter 2023 and Provides Corporate Update

    PYX-201 (a novel first-in-concept and first-in-class tumor stroma targeting antibody-drug conjugate [ADC] product candidate) Phase 1 trial progressing with fifth dose cohort at 3.6 mg/kg; data expected 1H 2024. PYX-106 (a fully human immunotherapy antibody candidate): Phase 1 trial now focusing on NSCLC and other tumor types; data expected 2H 2024. Cash runway extended to early 2026 due to cost reductions and portfolio prioritization, allows for preliminary data readouts from PYX-201 and PYX-106 programs. Balance sheet includes $134.4 million in cash, restricted cash, and short-term investments. BOSTON, Nov. 07, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-st

    11/7/23 4:30:00 PM ET
    $PYXS
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    Pyxis Oncology Reports Financial Results for Second-Quarter 2023 and Provides Corporate Update

    Third dose cohort initiated in Phase 1 trial of PYX-201, Pyxis Oncology's first ADC product candidate Preliminary data from two Phase 1 trials on track for late 2023 to early 2024 Apexigen transaction anticipated to close later in August Strong balance sheet with $144 million in cash (including restricted cash) and short-term investments supports operations into 1H 2025 BOSTON, Aug. 11, 2023 (GLOBE NEWSWIRE) --  Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company focused on developing next-generation therapeutics to target difficult-to-treat cancers, today reported financial results for the quarter ended June 30, 2023, and provided a corporate update. Pyxis Oncology ended the

    8/11/23 7:00:00 AM ET
    $PYXS
    Biotechnology: Pharmaceutical Preparations
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    Pyxis Oncology to Acquire Apexigen

    Pyxis Oncology positioned at forefront of Antibody-Drug Conjugate (ADC) development Commercially and clinically validated APXiMAB platform for antibody generation complements FACT ADC toolkit of linkers, payloads and conjugation chemistries previously obtained from Pfizer Sotigalimab, a potential best-in-class Phase 2 CD40 agonist, has demonstrated rapid, deep and durable responses across difficult-to-treat tumor types All-stock deal allows Pyxis Oncology to maintain cash runway into 1H 2025;PYX-201 and PYX-106 remain on track Webcast to be held today, May 24, at 9:00 a.m. ET BOSTON and SAN CARLOS, Calif., May 24, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. ("Pyx

    5/24/23 6:45:00 AM ET
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    Pyxis Oncology Reports Financial Results for the First Quarter 2023 and Provides Corporate Update

    Orphan Drug Designation received for PYX-201 in pancreatic cancer Preliminary data from two Phase 1 trials anticipated late 2023 to early 2024 Strong balance sheet with $150.8 million in cash (including restricted cash) and short-term investments and no debt supports operations into 1H 2025 BOSTON, May 11, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company focused on developing next-generation therapeutics to target difficult-to-treat cancers, today reported financial results for the quarter ended March 31, 2023, and provided a corporate update. Pyxis Oncology ended the first quarter of 2023 with approximately $150.8 million in cash, cash equivalents

    5/11/23 7:00:00 AM ET
    $PYXS
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    Pyxis Oncology Reports Financial Results for the Fiscal Year Ended December 31, 2022, and Provides Corporate Update

    Preliminary data from two Phase 1 trials anticipated late 2023 to early 2024 First subject dosed in Phase 1 trial of PYX-201; clinical sites being activated and patient screening underway in Phase 1 trial of PYX-106 Strong balance sheet with $180.7 million in cash (including restricted cash) and no debt as of year-end 2022 supports operations into 1H 2025 CAMBRIDGE, Mass., March 22, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company focused on developing next-generation therapeutics to target difficult-to-treat cancers, today reported financial results for the full year ended December 31, 2022, and provided a corporate update."Over the past year, our

    3/22/23 6:45:00 AM ET
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    Pyxis Oncology Inc. Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by Pyxis Oncology Inc.

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    11/12/24 11:53:51 AM ET
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    Amendment: SEC Form SC 13G/A filed by Pyxis Oncology Inc.

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    11/6/24 4:36:24 PM ET
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    SEC Form SC 13D/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13D/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    4/3/24 5:10:59 PM ET
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    SEC Form SC 13G filed by Pyxis Oncology Inc.

    SC 13G - Pyxis Oncology, Inc. (0001782223) (Subject)

    3/8/24 4:03:18 PM ET
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    SEC Form SC 13G/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    2/14/24 4:00:25 PM ET
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    SEC Form SC 13G/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    2/14/24 9:28:37 AM ET
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    SEC Form SC 13G filed by Pyxis Oncology Inc.

    SC 13G - Pyxis Oncology, Inc. (0001782223) (Subject)

    1/26/24 4:36:06 PM ET
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    SEC Form SC 13D/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13D/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    4/4/23 4:58:38 PM ET
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    SEC Form SC 13G/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    3/23/23 4:20:29 PM ET
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    SEC Form SC 13G/A filed by Pyxis Oncology Inc. (Amendment)

    SC 13G/A - Pyxis Oncology, Inc. (0001782223) (Subject)

    2/14/23 4:45:46 PM ET
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