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    SEC Form SC 13D/A filed by Erasca Inc. (Amendment)

    1/30/24 4:41:54 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ERAS alert in real time by email
    SC 13D/A 1 cormorant_sc13da.htm AMENDMENT NO. 3

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

     
    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 3)*

                                Erasca, Inc.                             
    (Name of Issuer)

                              Common Stock                          
    (Title of Class of Securities)

                                                            29479A108                                                        
    (CUSIP Number)

    Neb Obradovic
    Cormorant Asset Management, L.P.
    200 Clarendon Street, 52nd Floor
    Boston, MA 02116
    Tel. No.: 857-702-0386
    (Name, Address and Telephone Number of Person Authorized to
    Receive Notices and Communications)

                                November 29, 2023                           
     (Date of Event which Requires Filing of this Statement)

     
    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. [  ]
     
    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.
     
    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.
     
    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
     


    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.

    Cormorant Global Healthcare Master Fund, LP

    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    WC
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    Cayman Islands
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)
     
    9          Sole Dispositive Power
     
    0 shares

    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)
     
    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)
     
    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0%  (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)

    PN (Partnership)


    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.
     
    Cormorant Global Healthcare GP, LLC
     
    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    AF
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    Delaware
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)
     
    9          Sole Dispositive Power
     
    0 shares

    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)
     
    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)

    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0%  (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)
     
    OO (Limited Liability Company)


    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.
     
    Cormorant Private Healthcare Fund II, LP
     
    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    WC
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    Delaware
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)
     
    9          Sole Dispositive Power
     
    0 shares

    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)
     
    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)

    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0% (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)
     
    PN (Partnership)


    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.
     
    Cormorant Private Healthcare GP II, LLC

    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    AF
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    Delaware
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)
     
    9          Sole Dispositive Power
     
    0 shares

    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)
     
    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)

    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0%  (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)
     
    OO (Limited Liability Company)
     

    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.
     
    Cormorant Asset Management, LP
     
    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    AF
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    Delaware
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)
     
    9          Sole Dispositive Power
     
    0 shares

    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)

    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)

    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0%  (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)
     
    PN (Partnership)


    CUSIP NO.
    29479A108

    1
    Names of Reporting Persons.
     
    Bihua Chen
     
    2
    Check the Appropriate Box if a Member of a Group (See Instructions)
     
    (a)          [ ]
     
    (b)          [x]
    3
    SEC Use Only
    4
    Source of Funds (See Instructions):
    AF
    5
    Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e):
    [ ]
    6
    Citizenship or Place of Organization.
     
    United States
    Number
    of Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7          Sole Voting Power
     
    0 shares  (see Item 5 below)

    8          Shared Voting Power
     
    0 shares  (see Item 5 below)

    9          Sole Dispositive Power
     
    0 shares  (see Item 5 below)
     
    10          Shared Dispositive Power
     
    0 shares  (see Item 5 below)
     
    11
    Aggregate Amount Beneficially Owned by Each Reporting Person
     
    0 shares  (see Item 5 below)
     
    12
    Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)
        [ ] N/A
    13
    Percent of Class Represented by Amount in Row (9)*
     
    0% (see Item 5 below)
    14
    Type of Reporting Person (See Instructions)
     
    IN (Individual)


    AMENDMENT NO. 3 TO SCHEDULE 13D

    This Amendment No. 3 to Schedule 13D (this “Amendment”) relates to Common Stock of Erasca, Inc., a Delaware corporation (the “Issuer” or the “Company”).  The address of the principal executive offices of the Issuer is 3115 Merryfield Row, Suite 300, San Diego, California 92121. This Amendment is being filed by each of the Reporting Persons to amend the Schedule 13D that was filed on July 30, 2021, as amended on August 10, 2021 and December 21, 2022 (as amended, the “Schedule 13D”).  Unless otherwise indicated, all capitalized terms used herein but not defined herein shall have the same meaning as in the Schedule 13D.

    This amendment is being filed to amend and supplement Item 5 of the Schedule 13D.

    Item 5.  Interest in Securities of the Issuer

    Item 5 is hereby amended and supplemented as follows:

    (a) and (b)     See Items 7-13 on the cover pages.

    (c) The Reporting Persons effected the following transactions in the Company's Common Stock in the 60 day period beginning on the date requiring the filing of this Schedule 13D:
     
    Transaction
    Date
    No. Shares
    Avg. Price Per Share
    Open market sale
    November 28, 2023
    565,385
    $2.0145(1)(9)
    Open market sale
    November 29, 2023
    1,463,665
    $1.8048(2)(9)
    Open market sale
    November 30, 2023
    84,196
    $1.7059(3)(9)
    Open market sale
    December 1, 2023
    700,000
    $1.6105(4)(9)
    Open market sale
    December 1, 2023
    325,000
    $1.6802(5)(9)
    Open market sale
    December 4, 2023
    241,853
    $1.6662(6)(9)
    Open market sale
    December 5, 2023
    933,147
    $1.6816(7)(9)
    Open market sale
    December 6, 2023
    6,500,000
    $1.6552(8)(9)

    (1) Represents the weighted average sale price of Common Stock (the "shares") sold in a series of open market transactions on the transaction date at prices ranging from $1.99 to $2.055 per share.
    (2) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.80 to $1.985 per share.
    (3) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.70 to $1.72 per share.
    (4) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.55 to $1.67 per share.
    (5) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.68 to $1.70 per share.
    (6) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.65 to $1.70 per share.
    (7) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.65 to $1.825 per share.
    (8) Represents the weighted average sale price of the shares sold in a series of open market transactions on the transaction date at prices ranging from $1.65 to $1.75 per share.
    (9) The Reporting Persons undertake to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price of the transactions reported in this Schedule 13D.
     
    (d) Not applicable.
     
    (e) Not applicable.
     

    SIGNATURE
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete and correct.
     
    January 30, 2024
     

     
    CORMORANT GLOBAL HEALTHCARE
    MASTER FUND, LP
     
    By: Cormorant Global Healthcare GP, LLC
           its General Partner
       
     
    By: /s/ Bihua Chen
     
    Bihua Chen, Managing Member
       
     
    CORMORANT GLOBAL HEALTHCARE GP,
    LLC
       
     
    By: /s/ Bihua Chen
     
    Bihua Chen, Managing Member
       
     
    CORMORANT PRIVATE HEALTHCARE
    FUND II, LP
     
    By: Cormorant Private Healthcare GP II, LLC
           its General Partner
       
     
    By: /s/ Bihua Chen
     
    Bihua Chen, Managing Member
       
     
    CORMORANT PRIVATE HEALTHCARE GP
    II, LLC
       
     
    By: /s/ Bihua Chen
     
    Bihua Chen, Managing Member
       
     
    CORMORANT ASSET MANAGEMENT, LP
     
    By: Cormorant Asset Management GP, LLC
           its General Partner
       
     
    By: /s/ Bihua Chen
     
    Bihua Chen, Managing Member
       
     
    /s/ Bihua Chen
     
    Bihua Chen

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    Erasca Announces Positive Preliminary Phase 1 Dose Escalation Data for Potentially Best-in-Class Pan-RAS Molecular Glue ERAS-0015 in KRAS-Mutant Solid Tumors

    Robust monotherapy efficacy in KRAS G12X NSCLC: 62% uORR in 2L+ and 75% uORR in post-ICI/platinum 2/3L at 16-32 mg QD PAD, and 64% uORR in 2L+ at 24-32 mg QD RDE Robust monotherapy efficacy in 2L KRAS G12X PDAC: 40% uORR at 16-32 mg QD PAD, 42% uORR at 24-32 mg QD RDE, and 50% uORR at 32 mg QD Monotherapy generally well-tolerated with mostly low-grade AEs, no DLTs as of DCO, and low rate of dose reductions and no discontinuations due to TRAEs Preliminary data suggest ERAS-0015 may combine safely with standard-of-care doses of panitumumab with no DLTs as of DCO (N=3) and 1/1 uPR in CRC Well-behaved PK, with dose-dependent increase in PK exposure up to MAD of 40 mg QD and no exposure plate

    4/27/26 4:01:00 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Erasca to Host Conference Call and Webcast to Discuss Preliminary Phase 1 Dose Escalation Data for Potentially Best-in-Class Pan-RAS Molecular Glue ERAS-0015

    SAN DIEGO, April 27, 2026 (GLOBE NEWSWIRE) -- Erasca, Inc. (NASDAQ:ERAS), a clinical-stage precision oncology company singularly focused on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers, today announced that the Company will host a conference call and webcast to discuss preliminary Phase 1 dose escalation data for its potentially best-in-class pan-RAS molecular glue ERAS-0015 in patients with RAS-mutant solid tumors today, Monday, April 27, 2026, at 4:30 pm ET. Conference Call and Webcast InformationErasca will hold a conference call and webcast Monday, April 27, 2026, at 4:30 pm ET. The webcast link for the conference call is her

    4/27/26 8:30:00 AM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Erasca Announces Strategic In-Licensing of RAS-Targeting Franchise

    Pan-RAS molecular glue ERAS-0015 and pan-KRAS inhibitor ERAS-4001 are potent, oral inhibitors with potential best-in-class profiles in RASm solid tumors Pipeline prioritization and workforce restructuring sharpens focus on programs targeting the highest unmet needs and with highest probability of success Priced concurrent $160 million equity offering Erasca to host conference call and webcast Friday, May 17, 2024 at 8:30 am ET SAN DIEGO, May 16, 2024 (GLOBE NEWSWIRE) -- Erasca, Inc. (NASDAQ:ERAS), a clinical-stage precision oncology company singularly focused on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers, today anno

    5/16/24 8:02:00 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ERAS
    Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by Erasca Inc.

    SC 13G/A - Erasca, Inc. (0001761918) (Subject)

    11/14/24 5:13:04 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13G/A filed by Erasca Inc.

    SC 13G/A - Erasca, Inc. (0001761918) (Subject)

    11/14/24 4:04:32 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G filed by Erasca Inc.

    SC 13G - Erasca, Inc. (0001761918) (Subject)

    11/14/24 1:28:34 PM ET
    $ERAS
    Biotechnology: Pharmaceutical Preparations
    Health Care