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    SEC Form S-8 POS filed by Zynerba Pharmaceuticals Inc.

    10/11/23 9:22:57 AM ET
    $ZYNE
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ZYNE alert in real time by email
    S-8 POS 1 ny20011256x3-x12_s8pos.htm S-8 POS
    As filed with the Securities and Exchange Commission on October 11, 2023
    No. 333-272805
    No. 333-270891
    No. 333-263128
    No. 333-256028
    No. 333-237051
    No. 333-230182
    No. 333-223597
    No. 333-216967
    No. 333-216968
    No. 333-207973


    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549



    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-272805
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-270891
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-263128
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-256028
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-237051
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-230182
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-223597
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-216967
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-216968
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-207973

    UNDER
    THE SECURITIES ACT OF 1933



    ZYNERBA PHARMACEUTICALS, INC.
    (Exact name of registrant as specified in its charter)



    Delaware
     
    26-0389433
    (State or other jurisdiction of
    incorporation or organization)
     
    (I.R.S. Employer
    Identification No.)

    80 W. Lancaster Avenue, Suite 300
    Devon, PA 19333
    (484) 581-7505
    (Address of registrant’s principal executive offices)



    Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan
    Zynerba Pharmaceuticals, Inc. 2023 Stock Option and Incentive Plan
    Non-Qualified Stock Option Inducement Award
    (Full titles of the plans)



    Christian Ulrich
    Secretary
    80 W. Lancaster Avenue, Suite 300
    Devon, Pennsylvania 19333
    (484) 581-7505
    (Name, address and telephone number of agent for service)

    Copy To:
    William Intner
    Hogan Lovells US LLP
    100 International Drive
    Baltimore, MD 21202
    (410) 659-2700

    and to:
    Peter Cohen-Millstein
    Hogan Lovells US LLP
    390 Madison Avenue
    New York, NY 10017
    (212) 918-3000



    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

    Large accelerated filer
    ☐
     
    Accelerated filer
    ☐
    Non-accelerated filer
    ☒
     
    Smaller reporting company
    ☒
         
    Emerging growth company
    ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐




    EXPLANATORY NOTE

    This Post-Effective Amendment No. 1 relates to the following Registration Statements of Zynerba Pharmaceuticals, Inc. (the “Company”) on Form S-8 (collectively, the “Registration Statements”):

     
    •
    Registration Statement No. 333-207973, registering 1,854,161 shares of common stock of the Company, par value $0.001 per share (“Shares”), issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan., filed with the Securities and Exchange Commission (the “Commission”) on November 13, 2015;
         
     
    •
    Registration Statement No. 333-216967, registering 150,000 Shares, issuable pursuant to the Company’s Non-Qualified Stock Option Inducement Award, filed with the Commission on March 27, 2017;
         
     
    •
    Registration Statement No. 333-216968, registering 999,482 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 27, 2017;
         
     
    •
    Registration Statement No. 333-223597, registering 1,355,387 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 12, 2018;
         
     
    •
    Registration Statement No. 333-230182, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 11, 2019;
         
     
    •
    Registration Statement No. 333-237051, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 10, 2020;
         
     
    •
    Registration Statement No. 333-256028, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on May 12, 2021;
         
     
    •
    Registration Statement No. 333-263128, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 1, 2022;
         
     
    •
    Registration Statement No. 333-270891, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 28, 2023; and
         
     
    •
    Registration Statement No. 333-272805, registering 6,900,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. 2023 Stock Option and Incentive Plan, filed with the Commission on June 21, 2023.

    On August 14, 2023, the Company entered into an Agreement and Plan of Merger (the “Merger Agreement”) with Harmony Biosciences Holdings, Inc., a Delaware corporation (“Parent”) and Xylophone Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of Parent (“Purchaser”). Pursuant to the Merger Agreement, on October 10, 2023, Purchaser merged with and into the Company (the “Merger”), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

    In connection with the Merger, the offerings of securities pursuant to the Registration Statements have been terminated. In accordance with the undertakings made by the Company in the Registration Statements to remove from registration, by means of a post-effective amendment, any of the securities registered pursuant to the Registration Statements which remain unsold at the termination of the offerings, the Company hereby terminates the effectiveness of each Registration Statement and removes from registration all Shares registered under the Registration Statements that remain unsold as of the date hereof. Each Registration Statement is hereby amended, as appropriate, to reflect the deregistration of such securities. After giving effect to this Post-Effective Amendment No. 1 to the Registration Statements, there will be no remaining securities registered by the Company pursuant to the Registration Statements.



    SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, as amended, the Company certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Post-Effective Amendment No. 1 to the Registration Statements on Form S-8 to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Devon, Commonwealth of Pennsylvania, on October 11, 2023.

     
    ZYNERBA PHARMACEUTICALS, INC.
         
     
    By:
    /s/ Sandip Kapadia
     
    Name:
    Sandip Kapadia
     
    Title:
    President, Chief Executive Officer and Chief Financial Officer


    No other person is required to sign this Post-Effective Amendment No. 1 to the Registration Statements in reliance upon Rule 478 under the Securities Act of 1933, as amended.


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