• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 POS filed by Kezar Life Sciences Inc.

    5/11/26 4:10:50 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $KZR alert in real time by email
    S-8 POS 1 ef20072571_s8pos.htm S-8 POS
    As filed with the Securities and Exchange Commission on May 11, 2026

    Registration No. 333-225769
    Registration No. 333-230520
    Registration No. 333-237133
    Registration No. 333-254161
    Registration No. 333-263659
    Registration No. 333-271841
    Registration No. 333-277939
    Registration No. 333-286084


    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-225769
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-230520
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-237133
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-254161
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-263659
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-271841
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-277939
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO. 333-286084

    FORM S-8
    REGISTRATION STATEMENT
    UNDER
    THE SECURITIES ACT OF 1933


    KEZAR LIFE SCIENCES, INC.
    (Exact name of registrant as specified in its charter)


    Delaware
     
    47-3366145
    (State or other jurisdiction of incorporation or organization)
     
    (IRS employer identification number)

    4000 Shoreline Court, Suite 300
    South San Francisco, California 94080
    (Address of Principal Executive Offices, including Zip Code)


    Kezar Life Sciences, Inc. 2015 Equity Incentive Plan
    Kezar Life Sciences, Inc. 2018 Equity Incentive Plan
    Kezar Life Sciences, Inc. 2018 Employee Stock Purchase Plan
    Kezar Life Sciences, Inc. 2022 Inducement Plan

    (Full title of the Plans)


    Michael Hearne
    Chief Financial Officer
    Kezar Life Sciences, Inc.
    77 Upper Rock Circle, Suite 700
    Rockville, Maryland 20850
    (250) 744-2487
    (Name, Address and Telephone Number, including Area Code, of Agent for Service)

    Copies to:

    Andrew Marmer
    Jared Fertman
    Willkie Farr & Gallagher LLP
    787 Seventh Avenue
    New York, NY 10019-6099
    (212) 728-8000

    Bill Roegge
    Rita Sobral
    Cooley LLP
    55 Hudson Yards
    New York, NY 10001-2157
    (212) 479-6000



    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See definitions of “large accelerated filer, “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

    Large accelerated filer
    ☐
    Accelerated filer
    ☐



     
    Non-accelerated filer
    ☒
    Smaller reporting company
    ☒






    Emerging growth company
    ☐
     
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.  ☐



    EXPLANATORY NOTE
     
    DEREGISTRATION OF UNSOLD SECURITIES
     
    These Post-Effective Amendments (the “Post-Effective Amendments”) filed by Kezar Life Sciences, Inc., a Delaware corporation (the “Registrant”), to deregister all shares of the Registrant’s common stock, par value $0.001 per share (the “Shares”), remaining unissued under the following Registration Statements on Form S-8 (each, a “Registration Statement”, and collectively, the “Registration Statements”) filed by the Registrant with the U.S. Securities and Exchange Commission (the “Commission”).

     
    •
     
    Registration Statement on Form S-8 (No. 333-225769) pertaining to the registration of (i) 2,102,045 options issuable under the Kezar Life Sciences, Inc. 2015 Equity Incentive Plan (the “2015 Plan”), (ii) 1,845,465 Shares issuable under the Kezar Life Sciences, Inc. 2018 Equity Incentive Plan (the “2018 Plan”), (iii) 52,490 options issuable under the 2018 Plan and (iv) 200,000 Shares issuable under the Kezar Life Sciences, Inc. 2018 Employee Stock Purchase Plan (the “ESPP”).
     
    •
     
    Registration Statement on Form S-8 (No. 333-230520) pertaining to the registration of (i) 955,721 Shares issuable under the 2018 Plan and (ii) 191,144 Shares issuable under the ESPP.
     
    •
     
    Registration Statement on Form S-8 (No. 333-237133) pertaining to the registration of (i) 960,403 Shares issuable under the 2018 Plan and (ii) 192,080 Shares issuable under the ESPP.
     
    •
     
    Registration Statement on Form S-8 (No. 333-254161) pertaining to the registration of (i) 2,317,987 Shares issuable under the 2018 Plan and (ii) 375,000 Shares issuable under the ESPP.
     
    •
     
    Registration Statement on Form S-8 (No. 333-263659) pertaining to the registration of (i) 2,812,987 Shares issuable under the 2018 Plan and (ii) 375,000 Shares issuable under the ESPP.
     
    •
     
    Registration Statement on Form S-8 (No. 333-271841) pertaining to the registration of (i) 3,424,671 Shares issuable under the 2018 Plan, (ii) 1,995,000 Shares issuable under the Kezar Life Sciences, Inc. 2022 Inducement Plan (the “2022 Plan”) and (iii) 1,005,000 options under the 2022 Plan.
     
    •
     
    Registration Statement on Form S-8 (No. 333-277939) pertaining to the registration of 3,638,953 Shares issuable under the 2018 Plan.
     
    •
     
    Registration Statement on Form S-8 (No. 333-286084) pertaining to the registration of 365,181 Shares issuable under the 2018 Plan.
     
    The Registrant is filing these Post-Effective Amendments to withdraw and remove any unissued and unsold securities issuable by the Registrant pursuant to the above-referenced Registration Statements.
     
    On March 30, 2026, the Registrant entered into an Agreement and Plan of Merger (the “Merger Agreement”) with Aurinia Pharma U.S., Inc., a Delaware corporation (“Parent”), and Aurinia Merger Sub, Inc., a Delaware corporation and wholly owned subsidiary of Parent (“Merger Sub”). Pursuant to the Merger Agreement, on May 11, 2026, Merger Sub was merged with and into the Registrant with the Registrant surviving as a wholly owned subsidiary of Parent (the “Merger”). In the Merger, each share of common stock, par value $0.001 per share, of the Company (the “Shares”) (other than (i) Shares owned or held in the Company’s treasury immediately prior to the Effective Time, (ii) Shares owned directly or indirectly by Parent or Merger Sub immediately prior to the Effective Time and (iii) Shares held by any stockholder of the Registrant who properly exercised appraisal rights under Delaware law) was converted into the right to receive (i) $6.955 per Share in cash and (ii) one non-transferable contractual contingent value right for each Share.
     
    As a result of the Merger, the Registrant has terminated all offerings of its securities pursuant to the Registration Statements. In accordance with an undertaking made by the Registrant in each of the Registration Statements to remove from registration, by means of a post-effective amendment, any of the securities that had been registered for issuance that remain unsold at the termination of the offerings, the Registrant hereby removes from registration all such securities registered under the Registration Statements that remain unsold as of the date hereof and terminates the effectiveness of the Registration Statements.


    SIGNATURE
     
    Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing these Post-Effective Amendments to the Registration Statements and has duly caused these Post-Effective Amendments to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Rockville, State of Maryland, on May 11, 2026. No other person is required to sign these Post-Effective Amendments to the Registration Statements in reliance on Rule 478 of the Securities Act of 1933, as amended.


    KEZAR LIFE SCIENCES, INC.



    /s/ Michael Hearne

    Name: Michael Hearne

    Title: Chief Financial Officer



    Get the next $KZR alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $KZR

    DatePrice TargetRatingAnalyst
    10/17/2025$7.00Buy → Hold
    Jefferies
    10/17/2025Outperform → Mkt Perform
    William Blair
    8/11/2023$4.00Overweight → Equal Weight
    Wells Fargo
    3/16/2023Outperform → Mkt Perform
    William Blair
    12/8/2021$19.00Overweight
    Wells Fargo
    11/16/2021$12.00 → $20.00Buy
    HC Wainwright & Co.
    7/20/2021$14.00Buy
    JonesTrading
    More analyst ratings

    $KZR
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Aurinia Pharmaceuticals to Acquire Kezar Life Sciences for $6.955 in Cash per Share Plus a Contingent Value Right

    Aurinia Pharmaceuticals Inc. (NASDAQ:AUPH), a biopharmaceutical company focused on delivering therapies to people living with autoimmune diseases with high unmet medical needs, announced today it has entered into a definitive merger agreement (the "Merger Agreement") to acquire Kezar Life Sciences, Inc. (NASDAQ:KZR), a biotechnology company focusing on small-molecule therapeutics to treat unmet needs in autoimmunity and cancer, for $6.955 in cash per share of Kezar common stock, plus one non-transferable contingent value right ("CVR"), which represents the right to receive: (i) potential payments relating to the ongoing clinical development or disposition of zetomipzomib; (ii) certain proce

    3/30/26 8:00:00 AM ET
    $AUPH
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Enodia Therapeutics Strengthens Sec61 Portfolio Through Acquisition of Preclinical Assets from Kezar Life Sciences

    Transaction deepens insights into Sec61 selectivity for targeted protein degradation, supporting accelerated development of Enodia's novel small-molecule inhibitors Enodia Therapeutics, a biotechnology company developing novel small-molecule therapies for targeted protein degradation at the point of synthesis, and Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company developing novel small molecule therapeutics to treat unmet needs in immune-mediated diseases, today announced that Enodia has acquired Kezar's assets from its Sec61-based discovery and development program. The acquisition enables Enodia to advance its understanding of Sec61 selectivity mechanisms, ex

    3/12/26 9:00:00 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Life Sciences Announces Regulatory Update on Zetomipzomib Program in Autoimmune Hepatitis

    Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company developing novel small molecule therapeutics to treat unmet needs in immune-mediated diseases, today announced that the Food and Drug Administration (FDA) Division of Hepatology and Nutrition has granted Kezar a Type C meeting for the first quarter to discuss the development of zetomipzomib, a novel, selective inhibitor of the immunoproteasome, in patients with autoimmune hepatitis (AIH). The Type C meeting will involve review of a potential global, randomized Phase 2b clinical study of zetomipzomib in patients with relapsed and refractory AIH. As part of the briefing package submitted to the FDA, Kezar submitt

    1/9/26 6:01:00 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Kezar Life Sciences downgraded by Jefferies with a new price target

    Jefferies downgraded Kezar Life Sciences from Buy to Hold and set a new price target of $7.00

    10/17/25 8:25:43 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Life Sciences downgraded by William Blair

    William Blair downgraded Kezar Life Sciences from Outperform to Mkt Perform

    10/17/25 8:25:32 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Life Sciences downgraded by Wells Fargo with a new price target

    Wells Fargo downgraded Kezar Life Sciences from Overweight to Equal Weight and set a new price target of $4.00

    8/11/23 7:45:02 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Director Berger Franklin M closing all direct ownership in the company (SEC Form 4) to satisfy tax liability

    4 - Kezar Life Sciences, Inc. (0001645666) (Issuer)

    5/11/26 4:30:17 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Director Garner Elizabeth

    4 - Kezar Life Sciences, Inc. (0001645666) (Issuer)

    5/11/26 4:30:18 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Director Cooper Graham K

    4 - Kezar Life Sciences, Inc. (0001645666) (Issuer)

    5/11/26 4:30:19 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    SEC Filings

    View All

    SEC Form 15-12G filed by Kezar Life Sciences Inc.

    15-12G - Kezar Life Sciences, Inc. (0001645666) (Filer)

    5/21/26 6:01:35 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form EFFECT filed by Kezar Life Sciences Inc.

    EFFECT - Kezar Life Sciences, Inc. (0001645666) (Filer)

    5/15/26 12:15:05 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SCHEDULE 13D/A filed by Kezar Life Sciences Inc.

    SCHEDULE 13D/A - Kezar Life Sciences, Inc. (0001645666) (Subject)

    5/13/26 4:15:10 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    Leadership Updates

    Live Leadership Updates

    View All

    Kezar Life Sciences Announces Strategic Restructuring to Prioritize Clinical-Stage Assets and Extend Financial Runway and Appoints Christopher Kirk, Ph.D. as Chief Executive Officer

    Strategic realignment to focus capital resources on clinical programs and reduce workforce by approximately 41% Cash runway extended to fund PALIZADE global Phase 2b clinical trial evaluating zetomipzomib in lupus nephritis; topline data expected mid-2026 Co-Founder and Board Director, Christopher Kirk, PhD, appointed as Chief Executive Officer   Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company developing breakthrough treatments for immune-mediated and oncologic disorders, today announced it has initiated a strategic restructuring program to prioritize long-term growth and focus its resources on its clinical-stage programs. The strategic realignment

    10/3/23 4:10:00 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Life Sciences Reports Second Quarter 2022 Financial Results and Provides Business Update

    Announced positive topline results from the MISSION Phase 2 Trial evaluating zetomipzomib for the treatment of patients with lupus nephritis Appointed Nick Mordwinkin, Pharm.D., Ph.D. as Chief Business Officer Cash, cash equivalents and marketable securities totaled $306.8 million as of June 30, 2022 Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company discovering and developing breakthrough treatments for immune-mediated and oncologic disorders, today reported financial results for the second quarter ended June 30, 2022 and provided a business update. "The second quarter was tremendously productive for Kezar, during which we achieved key clinical milestone

    8/11/22 4:01:00 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Announces Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

    Kezar Life Sciences, Inc., (NASDAQ:KZR), a clinical-stage biotechnology company discovering and developing breakthrough treatments for immune-mediated and oncologic disorders, today announced that, in connection with the previously announced appointment of Nick Mordwinkin, Pharm.D., Ph.D., as the Company's Chief Business Officer, the Compensation Committee of the company's Board of Directors granted Dr. Mordwinkin a nonqualified stock option to purchase 200,000 shares of its common stock with an exercise price of $9.35 per share, which is equal to the closing price of Kezar's common stock on August 1, 2022. In addition, the Compensation Committee of the company's Board of Directors granted

    8/3/22 4:30:00 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    SEC Form SC 13D filed by Kezar Life Sciences Inc.

    SC 13D - Kezar Life Sciences, Inc. (0001645666) (Subject)

    10/8/24 4:20:17 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13G/A filed by Kezar Life Sciences Inc.

    SC 13G/A - Kezar Life Sciences, Inc. (0001645666) (Subject)

    7/8/24 4:32:39 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G/A filed by Kezar Life Sciences Inc. (Amendment)

    SC 13G/A - Kezar Life Sciences, Inc. (0001645666) (Subject)

    2/14/24 6:47:29 PM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $KZR
    Financials

    Live finance-specific insights

    View All

    Kezar Life Sciences Announces Positive Topline Results from the PORTOLA Phase 2a Trial Evaluating Zetomipzomib for the Treatment of Patients with Autoimmune Hepatitis (AIH) and Reports Fourth Quarter and Year End 2024 Financial Results

    Company-hosted conference call and webcast to be held today at 8:00 a.m. ET Zetomipzomib treatment results in steroid-sparing biochemical remissions in accordance with AASLD treatment guidelines in a difficult-to-treat, refractory AIH patient population. In relapsed, steroid-dependent AIH patients, of the 21 of 24 entering screening on steroid-based therapy, 36% (5 of 14) of zetomipzomib-treated patients achieved a complete biochemical response (CR) and clinically significant steroid taper to 5 mg/day or less, compared to 0 of 7 of placebo patients. In the intention-to-treat (ITT) population, 31% (5 of 16) of zetomipzomib patients achieved a CR and steroid taper (≤5 mg/day), compared

    3/25/25 7:30:00 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Board Unanimously Rejects Unsolicited Concentra Proposal and Adopts Limited Duration Stockholder Rights Plan

    Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company developing novel small molecule therapeutics to treat unmet needs in immune-mediated diseases, today announced that its Board of Directors (the "Board") has unanimously rejected the previously disclosed unsolicited, non-binding proposal from Concentra Biosciences, LLC ("Concentra") to acquire all of the outstanding shares of common stock of Kezar for cash consideration of $1.10 per share, plus a contingent value right that represents the right to receive 80% of the net proceeds from any out-license or disposition of Kezar's development programs or intellectual property. After careful consideration and with the a

    10/17/24 8:35:00 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Kezar Life Sciences to Change Virtual R&D Day Date to March 15, 2023

    Kezar Life Sciences, Inc. (NASDAQ:KZR), a clinical-stage biotechnology company discovering and developing breakthrough treatments for immune-mediated and oncologic disorders, today announced that the Company will pull forward its virtual Research and Development (R&D) Day to Wednesday, March 15, 2023 at 4:30 pm ET/1:30 pm PT. "The goal of Kezar's R&D Day is to set expectations for 2023, provide updates on our two clinical assets, and highlight the productivity from our Discovery team. We are progressing more quickly than planned with initiating PALIZADE, our next study of zetomipzomib for the treatment of lupus nephritis, and look forward to sharing the details," said John Fowler, Kezar's

    3/13/23 7:00:00 AM ET
    $KZR
    Biotechnology: Pharmaceutical Preparations
    Health Care