• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishDashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form 8-K filed by Spero Therapeutics Inc.

    6/18/25 5:12:45 PM ET
    $SPRO
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SPRO alert in real time by email
    8-K
    false 0001701108 0001701108 2025-06-12 2025-06-12
     
     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    FORM 8-K

     

     

    CURRENT REPORT

    Pursuant to Section 13 or 15(d)

    of The Securities Exchange Act of 1934

    Date of Report (Date of earliest event reported): June 12, 2025

     

     

    SPERO THERAPEUTICS, INC.

    (Exact name of registrant as specified in its charter)

     

     

     

    Delaware   001-38266   46-4590683

    (State or other jurisdiction

    of incorporation)

     

    (Commission

    File Number)

     

    (I.R.S. Employer

    Identification No.)

     

    675 Massachusetts Avenue, 14th Floor  
    Cambridge, Massachusetts   02139
    (Address of principal executive offices)   (Zip Code)

    Registrant’s telephone number, including area code (857) 242-1600

     

     

    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

     

    ☐

    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

     

    ☐

    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

     

    ☐

    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

     

    ☐

    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

    Securities registered pursuant to Section 12(b) of the Act:

     

    Title of each class

     

    Trading

    Symbol(s)

     

    Name of each exchange

    on which registered

    Common Stock, $0.001 par value   SPRO   The Nasdaq Global Select Market

    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

    Emerging growth company ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

     

     
     


    Item 5.02

    Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

    At the 2025 Annual Meeting of Stockholders (the “Annual Meeting”) of Spero Therapeutics, Inc. (the “Company”) held on June 12, 2025, the Company’s stockholders approved an amendment to the Company’s 2017 Stock Incentive Plan, as amended (the “2017 Plan”) to increase the total number of shares of the Company’s common stock authorized for issuance under the 2017 Plan by 3,000,000 shares.

    A detailed summary of the material features of the 2017 Plan, as amended, is set forth in the Company’s definitive proxy statement (the “Proxy Statement”) for its Annual Meeting filed with the Securities and Exchange Commission on April 28, 2025, which summary is incorporated herein by reference.

     

    Item 5.07

    Submission of Matters to a Vote of Stockholders

    On June 12, 2025, the Company held its Annual Meeting. Of the 55,910,641 shares of common stock issued and outstanding and eligible to vote as of the record date of April 21, 2025, a quorum of 40,015,633 shares, or approximately 71.57% of the outstanding shares, were present in person or by proxy.

    The following actions were taken at the Annual Meeting:

     

      1.

    The following nominees were reelected to serve on the Company’s board of directors as Class II directors until the Company’s 2028 annual meeting of stockholders, based on the following votes:

     

    Name

       Votes For    Votes Withheld    Broker Non-Votes

    Frank E. Thomas

       25,722,977    449,223    13,843,433

    Patrick Vink, M.D.

       23,247,371    2,924,829    13,843,433

    Esther Rajavelu

       25,678,198    494,002    13,843,433

     

      2.

    The selection of PricewaterhouseCoopers LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2025 was ratified, based on the following votes:

     

    Votes For

     

    Votes Against

     

    Votes Abstained

     

    Broker Non-Votes

    39,837,359   174,980   3,294   N/A

     

      3.

    The advisory vote of the compensation of the Company’s named executive officers, as described in the Proxy Statement, was approved, based on the following votes:

     

    Votes For

     

    Votes Against

     

    Votes Abstained

     

    Broker Non-Votes

    25,178,672   638,744   354,784   13,843,433

     

      4.

    The amendment to the 2017 Plan to increase the total number of shares of common stock authorized for issuance thereunder by 3,000,000 shares, was approved, based on the following votes:

     

    Votes For

     

    Votes Against

     

    Votes Abstained

     

    Broker Non-Votes

    22,965,487   3,154,609   52,104   13,843,433


    SIGNATURE

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

     

    Date: June 18, 2025     SPERO THERAPEUTICS, INC.
        By:  

    /s/ Esther Rajavelu

          Esther Rajavelu
          Chief Executive Officer, Chief Financial Officer and Chief Business Officer
    Get the next $SPRO alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $SPRO

    DatePrice TargetRatingAnalyst
    12/20/2024$5.00Outperform → In-line
    Evercore ISI
    9/23/2022$2.00 → $8.00In-line → Outperform
    Evercore ISI
    10/1/2021Outperform → Perform
    Oppenheimer
    More analyst ratings

    $SPRO
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Spero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study for Tebipenem HBr Stopped Early for Efficacy Following Review by Independent Data Monitoring Committee

      If approved, tebipenem HBr could be the first oral carbapenem antibiotic for US patients with complicated urinary tract infections (cUTIs) An estimated 2.9 million cases of cUTIs are treated annually in the US1 with many cases requiring hospitalization, contributing to over $6 billion per year in healthcare costs2Data from the PIVOT-PO trial to be part of a planned US Food and Drug Administration (FDA) filing in 2H 2025 that Spero's development partner, GSK, intends to submit CAMBRIDGE, Mass., May 28, 2025 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (NASDAQ:SPRO) and GSK plc (LSE/NYSE:GSK), today announced that the pivotal Phase 3 PIVOT-PO trial evaluating tebipenem HBr, an investigation

      5/28/25 7:00:00 AM ET
      $GSK
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics Announces First Quarter 2025 Operating Results and Provides a Business Update

      Pre-specified interim analysis of the ongoing Phase 3 PIVOT-PO clinical trial of tebipenem HBr in complicated urinary tract infection (cUTI), including acute pyelonephritis (AP), on track to be completed in Q2 2025Existing cash, together with earned development milestones from GSK, provide runway to fund operating expenses and capital expenditures into Q2 2026 CAMBRIDGE, Mass., May 13, 2025 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (NASDAQ:SPRO), a clinical-stage biopharmaceutical company, focused on identifying and developing novel treatments for rare diseases and multi-drug resistant (MDR) bacterial infections, today announced financial results for the first quarter ended March 31,

      5/13/25 4:01:00 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics to Report First Quarter 2025 Financial Results and Provide Business Update on Tuesday, May 13, 2025

      CAMBRIDGE, Mass., May 05, 2025 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (NASDAQ:SPRO), a clinical-stage biopharmaceutical company, focused on identifying and developing novel treatments for rare diseases and multi-drug resistant (MDR) bacterial infections, today announced that it will report its first quarter 2025 financial results and provide a business update on Tuesday, May 13, after the market close. The Company does not intend to host a conference call. About Spero TherapeuticsSpero Therapeutics, headquartered in Cambridge, Massachusetts, is a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare diseases and MDR bacterial infect

      5/5/25 8:00:00 AM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SPRO
    SEC Filings

    See more
    • SEC Form 8-K filed by Spero Therapeutics Inc.

      8-K - Spero Therapeutics, Inc. (0001701108) (Filer)

      6/18/25 5:12:45 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics Inc. filed SEC Form 8-K: Regulation FD Disclosure

      8-K - Spero Therapeutics, Inc. (0001701108) (Filer)

      5/28/25 7:12:40 AM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition

      8-K - Spero Therapeutics, Inc. (0001701108) (Filer)

      5/13/25 4:49:23 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SPRO
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Director Mahadevia Ankit was granted 20,000 shares, increasing direct ownership by 3% to 709,866 units (SEC Form 4)

      4 - Spero Therapeutics, Inc. (0001701108) (Issuer)

      6/16/25 8:32:05 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Deshpande Milind was granted 20,000 shares, increasing direct ownership by 28% to 91,454 units (SEC Form 4)

      4 - Spero Therapeutics, Inc. (0001701108) (Issuer)

      6/16/25 8:30:52 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Jackson Scott Thomas was granted 20,000 shares, increasing direct ownership by 36% to 75,000 units (SEC Form 4)

      4 - Spero Therapeutics, Inc. (0001701108) (Issuer)

      6/16/25 8:29:35 PM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SPRO
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Spero Therapeutics downgraded by Evercore ISI with a new price target

      Evercore ISI downgraded Spero Therapeutics from Outperform to In-line and set a new price target of $5.00

      12/20/24 7:51:16 AM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics upgraded by Evercore ISI with a new price target

      Evercore ISI upgraded Spero Therapeutics from In-line to Outperform and set a new price target of $8.00 from $2.00 previously

      9/23/22 7:52:34 AM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Spero Therapeutics downgraded by Oppenheimer

      Oppenheimer downgraded Spero Therapeutics from Outperform to Perform

      10/1/21 6:10:00 AM ET
      $SPRO
      Biotechnology: Pharmaceutical Preparations
      Health Care