• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Amendment: SEC Form SCHEDULE 13D/A filed by Edgewise Therapeutics Inc.

    4/27/26 4:49:16 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $EWTX alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 6)


    Edgewise Therapeutics, Inc.

    (Name of Issuer)


    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)




    28036F105

    (CUSIP Number)
    Barbara Fiorini
    Novo Holdings A/S, Tuborg Havnevej 19
    Hellerup, G7, DK-2900
    45 3527 6592

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
    04/23/2026

    (Date of Event Which Requires Filing of This Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




    schemaVersion:


    SCHEDULE 13D

    CUSIP Number(s):
    28036F105


    1 Name of reporting person

    Novo Holdings A/S
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DENMARK
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    5,350,000.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    5,350,000.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    5,350,000.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    4.9 %
    14Type of Reporting Person (See Instructions)

    CO



    SCHEDULE 13D

    Item 1.Security and Issuer
    (a)Title of Class of Securities:

    Common Stock, par value $0.0001 per share
    (b)Name of Issuer:

    Edgewise Therapeutics, Inc.
    (c)Address of Issuer's Principal Executive Offices:

    1715 38th St., Boulder, COLORADO , 80301.
    Item 1 Comment:
    This Amendment No. 6 (this "Amendment No. 6" or this "Schedule 13D/A") amends and supplements the statement on Schedule 13D originally filed with the Securities and Exchange Commission (the "SEC") on March 31, 2021, and amended on September 16, 2022, September 30, 2022, June 28, 2023, January 25, 2024 and September 23, 2024 (as amended, the "Statement") by the Reporting Person. This Amendment No. 6 is being filed to report the dilution of the Reporting Person's beneficial ownership in the Issuer's common stock and not as a result of any acquisition or disposition of securities by the Reporting Person. Unless otherwise defined herein, capitalized terms used in this Amendment No. 6 shall have the meanings ascribed to them in the Statement. Unless amended or supplemented below, the information in the Statement remains unchanged.
    Item 5.Interest in Securities of the Issuer
    (a)
    Novo Holdings A/S beneficially owns 5,350,000 shares of common stock representing approximately 4.98% of the Issuer's outstanding shares of common stock, based upon 107,532,173 shares of common stock outstanding as of April 9, 2026, as reported in the Issuer's definitive proxy statement, filed with the SEC on April 23, 2026. Due to field limitations of the EDGAR filing system, the percentage listed in Row 13 of the Reporting Person's cover page has been rounded down to 4.9%.
    (b)
    Novo Holdings A/S is a Danish corporation wholly owned by the Novo Nordisk Foundation. Novo Holdings A/S has the sole power to vote and dispose of the Novo Shares. Neither the Foundation nor any person listed on the updated Schedule I has the power to direct the vote as to, or the disposition of the Novo Shares.
    (c)
    Novo Holdings A/S has not effected any transactions in the Issuer's common stock within the past 60 days and neither the Foundation nor any person listed on the updated Schedule I has effected any transactions in the Issuer's common stock within the past 60 days.
    (d)
    Novo Holdings A/S does not know of any other person having the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Novo Shares.
    (e)
    The Reporting Person ceased to be the beneficial owner of more than five percent of the Common Stock on April 23, 2026.
    Item 7.Material to be Filed as Exhibits.
     
    Exhibit 99.1 Schedule I

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Novo Holdings A/S
     
    Signature:/s/ Barbara Fiorini
    Name/Title:By Barbara Fiorini, General Counsel, Finance & Operations
    Date:04/27/2026
    Get the next $EWTX alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $EWTX

    DatePrice TargetRatingAnalyst
    9/25/2025$20.00Neutral
    Goldman
    7/30/2025$46.00Strong Buy
    Raymond James
    6/30/2025$42.00Buy
    H.C. Wainwright
    4/30/2025$41.00Buy
    Guggenheim
    4/2/2025$14.00Sector Outperform → Sector Perform
    Scotiabank
    3/7/2025$50.00Sector Outperform
    Scotiabank
    1/22/2025$30.00Hold
    Stifel
    11/22/2024$45.00Outperform
    Evercore ISI
    More analyst ratings

    $EWTX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Goldman initiated coverage on Edgewise Therapeutics with a new price target

    Goldman initiated coverage of Edgewise Therapeutics with a rating of Neutral and set a new price target of $20.00

    9/25/25 8:29:56 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Raymond James initiated coverage on Edgewise Therapeutics with a new price target

    Raymond James initiated coverage of Edgewise Therapeutics with a rating of Strong Buy and set a new price target of $46.00

    7/30/25 7:32:57 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    H.C. Wainwright initiated coverage on Edgewise Therapeutics with a new price target

    H.C. Wainwright initiated coverage of Edgewise Therapeutics with a rating of Buy and set a new price target of $42.00

    6/30/25 8:01:12 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    SEC Filings

    View All

    SEC Form 8-K filed by Edgewise Therapeutics Inc.

    8-K - Edgewise Therapeutics, Inc. (0001710072) (Filer)

    6/1/26 8:51:21 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SCHEDULE 13G filed by Edgewise Therapeutics Inc.

    SCHEDULE 13G - Edgewise Therapeutics, Inc. (0001710072) (Subject)

    5/15/26 11:42:44 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form S-8 filed by Edgewise Therapeutics Inc.

    S-8 - Edgewise Therapeutics, Inc. (0001710072) (Filer)

    5/7/26 5:18:13 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Director Fox Jonathan C bought $199,403 worth of shares (10,700 units at $18.64), increasing direct ownership by 82% to 23,702 units (SEC Form 4)

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    11/13/25 6:04:59 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Thompson Peter A. bought $10,000,000 worth of shares (496,771 units at $20.13) (SEC Form 4)

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    4/4/25 7:42:30 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Orbimed Advisors Llc bought $10,000,000 worth of shares (496,771 units at $20.13) (SEC Form 4)

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    4/4/25 7:33:31 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Edgewise Therapeutics Reports Inducement Grants as permitted by the Nasdaq Listing Rules

    BOULDER, Colo., June 3, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. ("Edgewise" or the "Company"), (NASDAQ:EWTX), a leading muscle disease biopharmaceutical company developing novel therapeutics for muscular dystrophies and serious cardiac conditions, today announced that on May 29, 2026, Edgewise granted inducement stock options to purchase a total of 74,000 shares of Edgewise's common stock to 4 new non-executive employees in connection with the commencement of their employment, pursuant to Edgewise's 2024 Inducement Equity Incentive Plan (the "Inducement Plan").    Each

    6/3/26 4:01:00 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Edgewise Therapeutics Announces Sale of Sevasemten for Up to $2.65 Billion, Strengthening Balance Sheet and Centering Company Focus on Cardiovascular Pipeline

    — Edgewise to Receive $1.55 Billion in Upfront Cash Consideration and is Eligible to Receive up to $1.1 Billion in Regulatory and Commercial Milestones —— Transaction Creates Focused Cardiovascular Company with Enhanced Strategic Clarity —— Upfront Proceeds Expected to Fully Fund EDG-7500 Development Through Potential Approval —— On Track to Report 12-Week CIRRUS-HCM Part D Data in Q2 2026 —BOULDER, Colo., June 1, 2026 /PRNewswire/ -- Edgewise Therapeutics, Inc. (NASDAQ:EWTX), a leading muscle disease biopharmaceutical company, today announced that it has entered into a definitive agreement under which Servier, an independent international pharmaceutical group governed by a foundation, will

    6/1/26 8:30:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Servier to Acquire Edgewise Therapeutics' Muscular Dystrophy Business

    Acquisition supports Servier's strategic ambition in rare neurology for patients with high unmet medical needs.Transaction includes sevasemten, a late-stage investigational treatment for Becker and Duchenne muscular dystrophies. Transaction represents total value of up to $2.65 billion.SURESNES, France, June 1, 2026 /CNW/ -- Servier, an independent international pharmaceutical group governed by a foundation, today announced that it has entered into an agreement to acquire the muscular dystrophy business of Edgewise Therapeutics Inc. (NASDAQ:EWTX), a biopharmaceutical company focused on developing innovative therapies for serious muscle disorders, for up to $2.65 billion, including upfront pa

    6/1/26 8:30:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    CMO Donovan Joanne M. sold $2,092,063 worth of shares (55,230 units at $37.88) as part of a pre-agreed trading plan and exercised 50,000 shares at a strike of $7.08, decreasing direct ownership by 54% to 4,367 units (SEC Form 4)

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    5/5/26 1:15:09 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Fox Jonathan C

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    4/3/26 2:12:09 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Donovan Joanne M.

    4 - Edgewise Therapeutics, Inc. (0001710072) (Issuer)

    4/2/26 1:01:22 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Financials

    Live finance-specific insights

    View All

    Edgewise Therapeutics Announces Positive 4-Month Interim Results from the ARCH Open Label Study of EDG-5506 in Adults with Becker Muscular Dystrophy (BMD)

    – Remarkable North Star Ambulatory Assessment scale (NSAA) improvements relative to BMD natural history trajectories – – Significant decrease in levels of serum creatine kinase (CK) and fast skeletal muscle troponin I (TNNI2), enzyme biomarkers strongly associated with muscle damage caused by BMD – – EDG-5506 continues to be well-tolerated with no serious adverse events observed – – Management hosting webcast to discuss findings on September 12 at 8:30 a.m. Eastern Time – Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, small molecule therapies for the treatment of rare muscle disorders, announced today pos

    9/11/22 5:00:00 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Edgewise Therapeutics Announces Positive 2-Month Interim Results from the ARCH Open Label Study of EDG-5506 in Adults with Becker Muscular Dystrophy (BMD)

    – EDG-5506 treatment significantly lowered muscle damage biomarkers in adults with BMD – – BMD patients were more active during 2 months of dosing with EDG-5506 relative to activity measured in BMD patients in the Phase 1 study – – EDG-5506 was well tolerated with no serious adverse events observed; safety profile supported dose escalation to 15 mg daily for all patients – – Management hosting webcast to discuss findings on June 21 at 9:00 a.m. Eastern Time – Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, small molecule therapies for the treatment of rare muscle disorders, announced today positive 2-month

    6/20/22 8:00:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    New 2-Month Interim Data from the ARCH Open Label Study of EDG-5506 in Individuals with Becker Muscular Dystrophy (BMD) to be Presented at the Upcoming New Directions in Biology and Disease of Skeletal Muscle Conference

    - Edgewise management to host webcast conference call on Tuesday, June 21, 2022 at 9 a.m. Eastern Time - - Additional presentations and posters featuring EDG-5506 to be featured at the New Directions Conference and the upcoming PPMD Annual Conference - Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, small molecule therapies for rare muscle disorders, today announced that new 2-month interim data from the ARCH open label study of EDG-5506 in individuals with BMD will be presented at the 2022 New Directions in Biology and Disease of Skeletal Muscle Conference, being held June 20-23, 2022. Edgewise ARCH Interi

    6/16/22 8:00:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Leadership Updates

    Live Leadership Updates

    View All

    Edgewise Therapeutics Appoints Commercial Biotech Executive Christopher Martin to its Board of Directors

    BOULDER, Colo., Nov. 20, 2025 /PRNewswire/ -- Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a leading muscle disease biopharmaceutical company, today announced the appointment of biotechnology veteran Christopher Martin to its Board of Directors. Mr. Martin brings proven success across all key commercial functions, including marketing, sales, commercial operations, market access, trade and business development. "We are thrilled to welcome Chris to our Board of Directors," said Kevin Koch, Ph.D., President and Chief Executive Officer. "His commercial expertise and launch leadersh

    11/20/25 8:00:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Edgewise Therapeutics Announces Appointment of Michael Nofi as Chief Financial Officer, and the Retirement of Current CFO, R. Michael Carruthers

    BOULDER, Colo., Nov. 10, 2025 /PRNewswire/ -- Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a leading muscle disease biopharmaceutical company developing novel therapeutics for muscular dystrophies and serious cardiac conditions, today announced the appointment of Michael Nofi, as Chief Financial Officer (CFO), effective November 10, 2025. Mr. Nofi joins Edgewise after serving as Chief Accounting Officer (CAO) at SpringWorks Therapeutics, Inc. Mr. Nofi will succeed Edgewise CFO, R. Michael Carruthers, who is retiring. "As we enter a pivotal stage in our Company's evolution, we a

    11/10/25 8:00:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Edgewise Therapeutics Appoints Arlene Morris to its Board of Directors

    Edgewise Therapeutics, Inc., (NASDAQ:EWTX), a leading muscle disease biopharmaceutical company, today announced the appointment of biotechnology industry veteran Arlene Morris to its Board of Directors. Ms. Morris has extensive experience in the pharmaceutical and biotechnology industries serving in numerous executive management and board roles. "With over 30 years of exceptional leadership experience in the biotech industry, we are delighted to welcome Arlene to our Board," said Kevin Koch, Ph.D., President and Chief Executive Officer. "Arlene brings invaluable expertise in strategic development and operational excellence, and we are thankful to count her as a valued advisor as we contin

    5/7/24 8:00:00 AM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $EWTX
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13G/A filed by Edgewise Therapeutics Inc.

    SC 13G/A - Edgewise Therapeutics, Inc. (0001710072) (Subject)

    11/14/24 6:22:11 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13G/A filed by Edgewise Therapeutics Inc.

    SC 13G/A - Edgewise Therapeutics, Inc. (0001710072) (Subject)

    11/14/24 4:31:39 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G filed by Edgewise Therapeutics Inc.

    SC 13G - Edgewise Therapeutics, Inc. (0001710072) (Subject)

    11/14/24 4:14:38 PM ET
    $EWTX
    Biotechnology: Pharmaceutical Preparations
    Health Care